Twenty-four-hour movement guidelines during adolescence and midlife mortality

Adherence to 24-hour movement guidelines-which encompass regular physical activity, adequate sleep, and limited sedentary time1—significantly influences long-term health outcomes during adolescence and contributes holistically to overall health.2 However, its prospective relationship with midlife mortality remains unknown to date. Our aim was to determine the association between adherence to 24-hour movement guidelines during adolescence and premature mortality 26-27 years later. This aim was based on existing evidence3 suggesting a potential link between meeting these guidelines and reduced mortality risk among adults in an 11-year follow-up.