Prevalence of non-responders for glucose control markers after 10 weeks of high-intensity interval training in adult women with higher and lower insulin resistance
| dc.contributor.author | Álvarez, Cristian | |
| dc.contributor.author | Ramírez Campillo, Rodrigo | |
| dc.contributor.author | Ramírez Vélez, Robinson | |
| dc.contributor.author | Izquierdo Redín, Mikel | |
| dc.contributor.department | Ciencias de la Salud | es_ES |
| dc.contributor.department | Osasun Zientziak | eu |
| dc.date.accessioned | 2018-09-04T06:43:49Z | |
| dc.date.available | 2018-09-04T06:43:49Z | |
| dc.date.issued | 2017 | |
| dc.description.abstract | Background: Exercise training improves performance and biochemical parameters on average, but wide interindividual variability exists, with individuals classified as responders (R) or non-responders (NRs), especially between populations with higher or lower levels of insulin resistance. This study assessed the effects of high-intensity interval training (HIIT) and the prevalence of NRs in adult women with higher and lower levels of insulin resistance. Methods: Forty adult women were assigned to a HIIT program, and after training were analyzed in two groups; a group with higher insulin resistance (H-IR, 40 ± 6 years; BMI: 29.5 ± 3.7 kg/m2; n = 20) and a group with lower insulin resistance (L-IR, 35 ± 9 years; 27.8 ± 2.8 kg/m2; n = 20). Anthropometric, cardiovascular, metabolic, and performance variables were measured at baseline and after 10 weeks of training. Results: There were significant training-induced changes [delta percent (Δ%)] in fasting glucose, fasting insulin, and homeostasis model assessment of insulin resistance (HOMA-IR) scores in the H-IR group (−8.8, −26.5, −32.1%, p < 0.0001), whereas no significant changes were observed in the L-IR. Both groups showed significant pre-post changes in other anthropometric variables [waist circumference (−5.2, p < 0.010, and −3.8%, p = 0.046) and tricipital (−13.3, p < 0.010, and −13.6%, p < 0.0001), supra-iliac (−19.4, p < 0.0001, and −13.6%, p < 0.0001), and abdominal (−18.2, p < 0.0001, and −15.6%, p < 0.010) skinfold measurements]. Systolic blood pressure decreased significantly only in the L-IR group (−3.2%, p < 0.010). Both groups showed significant increases in 1RMLE (+12.9, p < 0.010, and +14.7%, p = 0.045). There were significant differences in the prevalence of NRs between the H-IR and L-IR groups for fasting glucose (25 vs. 95%, p < 0.0001) and fasting insulin (p = 0.025) but not for HOMA-IR (25 vs. 45%, p = 0.185). Conclusion: Independent of the “magnitude” of the cardiometabolic disease (i.e., higher vs. lower insulin resistance), no differences were observed in the NRs prevalence with regard to improved HOMA-IR or to anthropometric, cardiovascular, and muscle performance co-variables after 10 weeks of HIIT in sedentary adult women. This research demonstrates the protective effect of HIIT against cardiometabolic disease progression in a sedentary population. | en |
| dc.description.sponsorship | This work was supported by the health promotion program of the Public Health Service of Los Ríos Government (SSVV). MI was funded by research grants from the Spanish Net on Aging and frailty (RETICEF) (ISCIII, FEDER) and Centro de Investigación Biomédica en Red (CIBER) en Fragilidad y Envejecimiento Saludable (CIBERFES; CB16/10/00315) del Instituto de Salud Carlos III (FEDER). | en |
| dc.format.extent | 12 p. | |
| dc.format.mimetype | application/pdf | en |
| dc.identifier.doi | 10.3389/fphys.2017.00479 | |
| dc.identifier.issn | 1664-042X (Electronic) | |
| dc.identifier.uri | https://academica-e.unavarra.es/handle/2454/30436 | |
| dc.language.iso | eng | en |
| dc.publisher | Frontiers Media | en |
| dc.relation.ispartof | Frontiers in Physiology, 8: 479 | en |
| dc.relation.publisherversion | https://doi.org/10.3389/fphys.2017.00479 | |
| dc.rights | © 2017 Álvarez, Ramírez-Campillo, Ramírez-Vélez and Izquierdo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. | en |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess | |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
| dc.subject | High-intensity interval training | en |
| dc.subject | Non-responders | en |
| dc.subject | Insulin resistance | en |
| dc.subject | Women | en |
| dc.title | Prevalence of non-responders for glucose control markers after 10 weeks of high-intensity interval training in adult women with higher and lower insulin resistance | en |
| dc.type | info:eu-repo/semantics/article | |
| dc.type.version | info:eu-repo/semantics/publishedVersion | |
| dspace.entity.type | Publication | |
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