Publication: Lifestyle patterns and endocrine, metabolic, and immunological biomarkers in European adolescents: The HELENA study
| dc.contributor.author | Agostinis-Sobrinho, César | |
| dc.contributor.author | Gómez-Martínez, Sonia | |
| dc.contributor.author | Nova, Esther | |
| dc.contributor.author | Hernández, Aurora | |
| dc.contributor.author | Labayen Goñi, Idoia | |
| dc.contributor.author | Kafatos, Antonios | |
| dc.contributor.author | Gottand, Frederic | |
| dc.contributor.author | Molnár, Dénes | |
| dc.contributor.author | Ferrari, Marika | |
| dc.contributor.author | Moreno, Luis A. | |
| dc.contributor.department | Ciencias de la Salud | es_ES |
| dc.contributor.department | Osasun Zientziak | eu |
| dc.date.accessioned | 2019-06-25T08:05:47Z | |
| dc.date.available | 2019-11-15T00:00:14Z | |
| dc.date.issued | 2019 | |
| dc.description.abstract | Objective: To evaluate the association of lifestyle patterns related to physical activity (PA), sedentariness, and sleep with endocrine, metabolic, and immunological health biomarkers in European adolescents. Methods: The present cross-sectional study comprised 3528 adolescents (1845 girls) (12.5-17.5 years) enrolled in the Healthy Lifestyle in Europe by Nutrition in Adolescence Study. Cluster analysis was performed by including body composition, PA by accelerometry, self-reported sedentary behaviors, and sleep duration. We also measured endocrine, metabolic, and immunological biomarkers. Results: Three-cluster solutions were identified: (a) light-PA time, moderate-vigorous-PA time and sedentary time, (b) light-PA time, moderate-vigorous-PA time, sedentary time and sleep time, (c) light-PA time, moderate-vigorous-PA time, sedentary time and body composition. In addition, each cluster solution was defined as: “healthy,” “medium healthy,” and “unhealthy” according to the presented rating. Analysis of variance showed that overall the healthiest groups from the three clusters analyzed presented a better metabolic profile. A decision tree analysis showed that leptin had a strong association with cluster 3 in both boys and girls, high-density lipoprotein cholesterol had the strongest association with clusters 1 and 3 in boys. Cortisol had the strongest association with cluster 1. HOMA index (homeostatic model assessment) and C3 showed a strong association with cluster 3 in girls. Conclusions: Our results support the existence of different interactions between metabolic health and lifestyle patterns related to PA, sedentariness, and sleep, with some gender-specific findings. These results highlight the importance to consider multiple lifestyle-related health factors in the assessment of adolescents' health to plan favorable strategies. | en |
| dc.description.sponsorship | The HELENA Study was carried out with the financial support of the European Community Sixth RTD Framework Programme (Contract FOODCT-2005-007034). The study was partially supported by the Redes temáticas de Investigación Cooperativa RETIC (Red SAMID RD16/0022), and by the University of Granada, Plan Propio de Investigación 2016, Excellence actions: Units of Excellence; Unit of Excellence on Exercise and Health (UCEES). | en |
| dc.embargo.lift | 2019-11-15 | |
| dc.embargo.terms | 2019-11-15 | |
| dc.format.extent | 29 p. | |
| dc.format.mimetype | application/pdf | en |
| dc.identifier.doi | 10.1111/pedi.12802 | |
| dc.identifier.issn | 1399-543X | |
| dc.identifier.uri | https://academica-e.unavarra.es/handle/2454/33497 | |
| dc.language.iso | eng | en |
| dc.publisher | Wiley | en |
| dc.relation.ispartof | Pediatric Diabetes, 2019; 20: 23 –31 | en |
| dc.relation.publisherversion | https://doi.org/10.1111/pedi.12802 | |
| dc.rights | © 2018 John Wiley & Sons A/S | en |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess | en |
| dc.rights.accessRights | Acceso abierto / Sarbide irekia | es |
| dc.subject | Cardiometabolic biomarkers | en |
| dc.subject | Physical activity | en |
| dc.subject | Sedentary behavior | en |
| dc.subject | Sleep time | en |
| dc.subject | Youth | en |
| dc.title | Lifestyle patterns and endocrine, metabolic, and immunological biomarkers in European adolescents: The HELENA study | en |
| dc.type | info:eu-repo/semantics/article | en |
| dc.type | Artículo / Artikulua | es |
| dc.type.version | info:eu-repo/semantics/acceptedVersion | en |
| dc.type.version | Versión aceptada / Onetsi den bertsioa | es |
| dspace.entity.type | Publication | |
| relation.isAuthorOfPublication | b36e2b1d-3088-4089-806e-fd3040e9583a | |
| relation.isAuthorOfPublication.latestForDiscovery | b36e2b1d-3088-4089-806e-fd3040e9583a |