Iflavirus increases its infectivity and physical stability in association with baculovirus

Jakubowska, Agata; Murillo Pérez, Rosa; Carballo Palos, Arkaitz; Williams, Trevor; Lent, Jan W. M. van; Caballero Murillo, Primitivo; Herrero, Salvador

Publication:
Iflavirus increases its infectivity and physical stability in association with baculovirus

dc.contributor.author	Jakubowska, Agata
dc.contributor.author	Murillo Pérez, Rosa
dc.contributor.author	Carballo Palos, Arkaitz
dc.contributor.author	Williams, Trevor
dc.contributor.author	Lent, Jan W. M. van
dc.contributor.author	Caballero Murillo, Primitivo
dc.contributor.author	Herrero, Salvador
dc.contributor.department	Nekazaritza Ekoizpena	eu
dc.contributor.department	Producción Agraria	es_ES
dc.contributor.department	IdAB. Instituto de Agrobiotecnología / Agrobioteknologiako Institutua	es_ES
dc.date.accessioned	2018-09-06T12:20:15Z
dc.date.available	2018-09-06T12:20:15Z
dc.date.issued	2016
dc.description.abstract	Virus transmission and the prevalence of infection depend on multiple factors, including the interaction with other viral pathogens infecting the same host. In this study, active replication of an iflavirus, Spodoptera exigua iflavirus 1 (order Picornavirales) was observed in the offspring of insects that survived following inoculation with a pathogenic baculovirus, Spodoptera exigua multiple nucleopolyhedrovirus. Tracking the origin of the iflavirus suggested the association of this virus with the occlusion bodies of the baculovirus. Here we investigated the effect of this association on the stability and infectivity of both viruses. A reduction in baculovirus pathogenicity, without affecting its infectivity and productivity, was observed when associated with the iflavirus. In contrast, viral association increased the infectivity of the iflavirus and its resistance to ultraviolet radiation and high temperature, two of the main factors affecting virus stability in the field. In addition, electron microscopy analysis revealed the presence of particles resembling iflavirus virions inside the occlusion bodies of the baculovirus, suggesting the possible co-occlusion of both viruses. Results reported here are indicative of facultative phoresis of a virus and suggest that virus virus interactions may be more common than currently recognized, and may be influential in the ecology of baculovirus and host populations and in consequence in the use of baculoviruses as biological insecticides.	en
dc.description.sponsorship	This study received financial support from the Spanish Ministry for Science and Technology (AGL2011-30352-C02 and AGL2014-57752-C2).	en
dc.format.mimetype	application/pdf	en
dc.format.mimetype	application/zip	en
dc.identifier.doi	10.7717/peerj.1687
dc.identifier.issn	2167-8359
dc.identifier.uri	https://academica-e.unavarra.es/handle/2454/30534
dc.language.iso	eng	en
dc.publisher	PeerJ	en
dc.relation.ispartof	PeerJ, 4:e1687	en
dc.relation.projectID	info:eu-repo/grantAgreement/MICINN//AGL2011-30352-C02-01/ES/	en
dc.relation.projectID	info:eu-repo/grantAgreement/MINECO//AGL2014-57752-C2-1-R/ES/	en
dc.relation.publisherversion	https://doi.org/10.7717/peerj.1687
dc.rights	© 2016 Jakubowska et al. Distributed under Creative Commons CC-BY 4.0	en
dc.rights.accessRights	info:eu-repo/semantics/openAccess	en
dc.rights.accessRights	Acceso abierto / Sarbide irekia	es
dc.rights.uri	https://creativecommons.org/licenses/by/4.0/
dc.subject	Iflavirus	en
dc.subject	Baculovirus	en
dc.subject	Virus parasitism	en
dc.subject	Insect virus	en
dc.subject	Co-infection	en
dc.subject	Virus virus interaction	en
dc.title	Iflavirus increases its infectivity and physical stability in association with baculovirus	en
dc.type	info:eu-repo/semantics/article
dc.type.version	info:eu-repo/semantics/publishedVersion	en
dc.type.version	Versión publicada / Argitaratu den bertsioa	es
dspace.entity.type	Publication
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