Relationship between handgrip strength and muscle mass in female survivors of breast cancer: a mediation analysis
| dc.contributor.author | Benavides Rodríguez, Lorena | |
| dc.contributor.author | García Hermoso, Antonio | |
| dc.contributor.author | Rodrigues Bezerra, Diogo | |
| dc.contributor.author | Izquierdo Redín, Mikel | |
| dc.contributor.author | Correa Bautista, Jorge Enrique | |
| dc.contributor.author | Ramírez Vélez, Robinson | |
| dc.contributor.department | Ciencias de la Salud | es_ES |
| dc.contributor.department | Osasun Zientziak | eu |
| dc.date.accessioned | 2018-09-06T12:20:13Z | |
| dc.date.available | 2018-09-06T12:20:13Z | |
| dc.date.issued | 2017 | |
| dc.description.abstract | This study explored the mediating factors of sarcopenia in a group of women survivors of breast cancer in Bogotá, Colombia. This was a descriptive cross-sectional study with 98 women survivors of breast cancer, who were registered with the SIMMON (Integrated Synergies to Improve Oncological Management in Colombia) Foundation. Body weight, height, and waist circumference (WC) were measured, and body mass index (BMI) was calculated. Body composition (percentage of fat and muscle mass) was evaluated via four-pole bioelectrical impedance analysis. Sarcopenia was defined as low muscle mass plus low grip strength or low gait speed (European Working Group on Sarcopenia in Older People (EWGSOP) criteria). A “causal” mediation analysis with the Baron & Kenny procedure (PROCESS® macro, Columbus, OH, USA) was used to explore variables related to sarcopenia. Analyses were performed with the IBM SPSS 21 statistical package (SPSS Inc., Chicago, IL, USA). The significance level of the results obtained in the hypothesis contrast was p < 0.05. The mean age of the sample was 65.5 ± 5.9 years, with a BMI of 27.8 ± 4.7 kg/m2. The prevalence of sarcopenia was 22.4%. Linear regression models suggest a partial mediation of anthropometric parameters (body mass, body mass index and waist circumference) in the association between handgrip strength and muscle mass. In conclusion, one in every five women survivors of breast cancer had sarcopenia. The findings seem to emphasize the importance of obesity prevention in women survivors of breast cancer, suggesting that high handgrip strength may not relate closely to greater muscle mass and therefore would not exclude the risk of sarcopenia. | en |
| dc.description.sponsorship | The authors thank the Centro de Estudios en Medición de la Actividad Física (CEMA) at Universidad del Rosario for the financial and scientific support, respectively. Also, during the completion of this paper, Antonio Garcia-Hermoso was visiting researchers at the University of Rosario (CEMA, Bogotá, Colombia), supported with grants awarded by Proyectos Basales y Vicerrectoría de Investigación, Desarrollo e Innovación (Universidad de Santiago de Chile, USACH). | en |
| dc.format.mimetype | application/pdf | en |
| dc.identifier.doi | 10.3390/nu9070695 | |
| dc.identifier.issn | 2072-6643 | |
| dc.identifier.uri | https://academica-e.unavarra.es/handle/2454/30529 | |
| dc.language.iso | eng | en |
| dc.publisher | MDPI | en |
| dc.relation.ispartof | Nutrients, 2017, 9, 695 | en |
| dc.relation.publisherversion | https://doi.org/10.3390/nu9070695 | |
| dc.rights | © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) | en |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess | |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
| dc.subject | Prevalence | en |
| dc.subject | Body composition | en |
| dc.subject | Sarcopenia | en |
| dc.subject | Breast cancer | en |
| dc.subject | Physical performance | en |
| dc.subject | Adults | en |
| dc.title | Relationship between handgrip strength and muscle mass in female survivors of breast cancer: a mediation analysis | en |
| dc.type | info:eu-repo/semantics/article | |
| dc.type.version | info:eu-repo/semantics/publishedVersion | |
| dspace.entity.type | Publication | |
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