LysM proteins in mammalian fungal pathogens
| dc.contributor.author | Oguiza Tomé, José Antonio | |
| dc.contributor.department | Institute for Multidisciplinary Research in Applied Biology - IMAB | en |
| dc.contributor.funder | Universidad Pública de Navarra / Nafarroako Unibertsitate Publikoa | es |
| dc.date.accessioned | 2022-09-05T07:46:20Z | |
| dc.date.available | 2022-09-05T07:46:20Z | |
| dc.date.issued | 2022 | |
| dc.date.updated | 2022-09-05T07:46:20Z | |
| dc.description.abstract | The LysM domain is a highly conserved carbohydrate-binding module that recognizes polysaccharides containing N-acetylglucosamine residues. LysM domains are found in a wide variety of extracellular proteins and receptors from viruses, bacteria, fungi, plants and animals. LysM proteins are also present in many species of mammalian fungal pathogens, although a limited number of studies have focused on the expression and determination of their putative roles in the infection process. This review summarizes the current knowledge and recent studies on LysM proteins in the main morphological groups of fungal pathogens that cause infections in humans and other mammals. Recent advances towards understanding the biological functions of LysM proteins in infections of mammalian hosts and their use as potential targets in antifungal strategies are also discussed. | en |
| dc.description.sponsorship | This work was supported by research project RTI2018-099371-B-I00 of the Spanish National Research Plan and by additional institutional support from the Public University of Navarre. | en |
| dc.format.mimetype | application/pdf | en |
| dc.identifier.citation | Oguiza, J. A.. (2022). LysM proteins in mammalian fungal pathogens. Fungal Biology Reviews. Vol. 40, pp. 114-122 | en |
| dc.identifier.doi | 10.1016/j.fbr.2022.02.001 | |
| dc.identifier.issn | 1749-4613 | |
| dc.identifier.uri | https://academica-e.unavarra.es/handle/2454/43950 | |
| dc.language.iso | eng | en |
| dc.publisher | Elsevier | en |
| dc.relation.ispartof | Fungal Biology Reviews, 2022, vol. 40,pp. 114-122 | en |
| dc.relation.projectID | info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RTI2018-099371-B-I00/ES/ | |
| dc.relation.publisherversion | https://doi.org/10.1016/j.fbr.2022.02.001 | |
| dc.rights | © 2022 The Author(s). This is an open access article under the CC BY license | en |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess | |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
| dc.subject | Chitinase | en |
| dc.subject | Effector | en |
| dc.subject | Fungal virulence | en |
| dc.subject | Fungi | en |
| dc.subject | LysM | en |
| dc.subject | Mammalian pathogen | en |
| dc.title | LysM proteins in mammalian fungal pathogens | en |
| dc.type | info:eu-repo/semantics/article | |
| dc.type.version | info:eu-repo/semantics/publishedVersion | |
| dspace.entity.type | Publication | |
| relation.isAuthorOfPublication | 0a109d77-5b6c-41ee-b859-c75cc8b012ed | |
| relation.isAuthorOfPublication.latestForDiscovery | 0a109d77-5b6c-41ee-b859-c75cc8b012ed |