LysM proteins in mammalian fungal pathogens

dc.contributor.authorOguiza Tomé, José Antonio
dc.contributor.departmentInstitute for Multidisciplinary Research in Applied Biology - IMABen
dc.contributor.funderUniversidad Pública de Navarra / Nafarroako Unibertsitate Publikoaes
dc.date.accessioned2022-09-05T07:46:20Z
dc.date.available2022-09-05T07:46:20Z
dc.date.issued2022
dc.date.updated2022-09-05T07:46:20Z
dc.description.abstractThe LysM domain is a highly conserved carbohydrate-binding module that recognizes polysaccharides containing N-acetylglucosamine residues. LysM domains are found in a wide variety of extracellular proteins and receptors from viruses, bacteria, fungi, plants and animals. LysM proteins are also present in many species of mammalian fungal pathogens, although a limited number of studies have focused on the expression and determination of their putative roles in the infection process. This review summarizes the current knowledge and recent studies on LysM proteins in the main morphological groups of fungal pathogens that cause infections in humans and other mammals. Recent advances towards understanding the biological functions of LysM proteins in infections of mammalian hosts and their use as potential targets in antifungal strategies are also discussed.en
dc.description.sponsorshipThis work was supported by research project RTI2018-099371-B-I00 of the Spanish National Research Plan and by additional institutional support from the Public University of Navarre.en
dc.format.mimetypeapplication/pdfen
dc.identifier.citationOguiza, J. A.. (2022). LysM proteins in mammalian fungal pathogens. Fungal Biology Reviews. Vol. 40, pp. 114-122en
dc.identifier.doi10.1016/j.fbr.2022.02.001
dc.identifier.issn1749-4613
dc.identifier.urihttps://academica-e.unavarra.es/handle/2454/43950
dc.language.isoengen
dc.publisherElsevieren
dc.relation.ispartofFungal Biology Reviews, 2022, vol. 40,pp. 114-122en
dc.relation.projectIDinfo:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RTI2018-099371-B-I00/ES/
dc.relation.publisherversionhttps://doi.org/10.1016/j.fbr.2022.02.001
dc.rights© 2022 The Author(s). This is an open access article under the CC BY licenseen
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectChitinaseen
dc.subjectEffectoren
dc.subjectFungal virulenceen
dc.subjectFungien
dc.subjectLysMen
dc.subjectMammalian pathogenen
dc.titleLysM proteins in mammalian fungal pathogensen
dc.typeinfo:eu-repo/semantics/article
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dspace.entity.typePublication
relation.isAuthorOfPublication0a109d77-5b6c-41ee-b859-c75cc8b012ed
relation.isAuthorOfPublication.latestForDiscovery0a109d77-5b6c-41ee-b859-c75cc8b012ed

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