Malnutrition and poor physical function are associated with higher comorbidity index in hospitalized older adults
| dc.contributor.author | Amasene, María | |
| dc.contributor.author | Medrano Echeverría, María | |
| dc.contributor.author | Echeverría, Iñaki | |
| dc.contributor.author | Urquiza, Miriam | |
| dc.contributor.author | Rodríguez Larrad, Ana | |
| dc.contributor.author | Díez, Amaia | |
| dc.contributor.author | Labayen Goñi, Idoia | |
| dc.contributor.author | Besga, Ariadna | |
| dc.contributor.department | Institute on Innovation and Sustainable Development in Food Chain - ISFOOD | en |
| dc.date.accessioned | 2023-01-16T11:01:02Z | |
| dc.date.available | 2023-01-16T11:01:02Z | |
| dc.date.issued | 2022 | |
| dc.date.updated | 2023-01-16T10:50:08Z | |
| dc.description.abstract | Background: The Charlson Comorbidity Index (CCI) is the most widely used method to measure comorbidity and predict mortality. There is no evidence whether malnutrition and/or poor physical function are associated with higher CCI in hospitalized patients. Therefore, this study aimed to (i) analyze the association between the CCI with nutritional status and with physical function of hospitalized older adults and (ii) examine the individual and combined associations of nutritional status and physical function of older inpatients with comorbidity risk. Methods: A total of 597 hospitalized older adults (84.3 ± 6.8 years, 50.3% women) were assessed for CCI, nutritional status (the Mini Nutritional Assessment-Short Form [MNA-SF]), and physical function (handgrip strength and the Short Physical Performance Battery [SPPB]). Results: Better nutritional status (p < 0.05) and performance with handgrip strength and the SPPB were significantly associated with lower CCI scores among both men (p < 0.005) and women (p < 0.001). Patients with malnutrition or risk of malnutrition (OR: 2.165, 95% CI: 1.408–3.331, p < 0.001) as well as frailty (OR: 3.918, 95% CI: 2.326–6.600, p < 0.001) had significantly increased the risk for being at severe risk of comorbidity. Patients at risk of malnutrition or that are malnourished had higher CCI scores regardless of being fit or unfit according to handgrip strength (p for trend <0.05), and patients classified as frail had higher CCI despite their nutritional status (p for trend <0.001). Conclusions: The current study reinforces the use of the MNA-SF and the SPPB in geriatric hospital patients as they might help to predict poor clinical outcomes and thus indirectly predict post-discharge mortality risk. | en |
| dc.description.sponsorship | This study was supported by the Basque Government (2016111138). MA was supported by a grant from the University of the Basque Country (PIF17/186) and IE was supported by a grant from the University of the Basque Country in collaboration with the University of Bordeaux (UBX) (PIFBUR16/07). | en |
| dc.format.mimetype | application/pdf | en |
| dc.identifier.citation | Amasene, M., Medrano, M., Echeverria, I., Urquiza, M., Rodriguez-Larrad, A., Diez, A., Labayen, I., & Ariadna, B.-B. (2022). Malnutrition and poor physical function are associated with higher comorbidity index in hospitalized older adults. Frontiers in Nutrition, 9, 920485. https://doi.org/10.3389/fnut.2022.920485 | en |
| dc.identifier.doi | 10.3389/fnut.2022.920485 | |
| dc.identifier.issn | 2296-861X | |
| dc.identifier.uri | https://academica-e.unavarra.es/handle/2454/44561 | |
| dc.language.iso | eng | en |
| dc.publisher | Frontiers Media | en |
| dc.relation.ispartof | Frontiers in Nutrition 2022, 9 (920485) | en |
| dc.relation.publisherversion | https://doi.org/10.3389/fnut.2022.920485 | |
| dc.rights | © 2022 Amasene, Medrano, Echeverria, Urquiza, Rodriguez-Larrad, Diez, Labayen and Ariadna. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. | en |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess | |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
| dc.subject | Chronic diseases | en |
| dc.subject | Geriatrics | en |
| dc.subject | Inpatients | en |
| dc.subject | Mortality | en |
| dc.subject | Muscle strength | en |
| dc.subject | Nutritional status | en |
| dc.title | Malnutrition and poor physical function are associated with higher comorbidity index in hospitalized older adults | en |
| dc.type | info:eu-repo/semantics/article | |
| dc.type.version | info:eu-repo/semantics/publishedVersion | |
| dspace.entity.type | Publication | |
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