Mediterranean diet-based interventions to improve anthropometric and obesity indicators in children and adolescents: a systematic review with meta-analysis of randomized controlled trials

López Gil, José Francisco; García Hermoso, Antonio; Sotos-Prieto, Mercedes; Cavero-Redondo, Iván; Martínez Vizcaíno, Vicente; Kales, Stefanos N.

Mediterranean diet-based interventions to improve anthropometric and obesity indicators in children and adolescents: a systematic review with meta-analysis of randomized controlled trials

dc.contributor.author	López Gil, José Francisco
dc.contributor.author	García Hermoso, Antonio
dc.contributor.author	Sotos-Prieto, Mercedes
dc.contributor.author	Cavero-Redondo, Iván
dc.contributor.author	Martínez Vizcaíno, Vicente
dc.contributor.author	Kales, Stefanos N.
dc.contributor.department	Ciencias de la Salud	es_ES
dc.contributor.department	Osasun Zientziak	eu
dc.contributor.funder	Universidad Pública de Navarra / Nafarroako Unibertsitate Publikoa, 1225%2F2022	es
dc.date.accessioned	2023-10-17T11:23:48Z
dc.date.available	2023-10-17T11:23:48Z
dc.date.issued	2023
dc.date.updated	2023-10-17T11:05:26Z
dc.description.abstract	To our knowledge, no systematic review with meta-analysis has separately synthesized the effects of Mediterranean diet-based interventions in children and adolescents in relation to the effects on anthropometric measures. A better understanding of the effects of Mediterranean dietbased interventions on anthropometric variables could facilitate their implementation in efforts to prevent obesity in the young population. The aim of the present meta-analysis was to evaluate the effects of Mediterranean diet-based interventions on anthropometric and obesity indicators among children and adolescents. Four databases were systematically searched (PubMed, Scopus, Web of Science, and Cochrane Database of Systematic Reviews), including all studies up until 15 March, 2023. Eligible articles were randomized controlled trials measuring the effect of an intervention based on the promotion of the Mediterranean diet and obesity-associated parameters. The effect size of each study was estimated by Cohen’s d for continuous variables or risk difference for categorical variables. Compared to the control group, the Mediterranean diet-based interventions showed small and significant reductions in body mass index (d=- 0.14; 95% CI: 0.26, 0.01; I 2= 77.52%). Participants in the Mediterranean diet-based interventions had a significant reduction in the percentage of obesity (risk difference = 0.12; 95% CI: 0.01, 0.23; I 2= 84.56%) in comparison with the control group. Interventions had greater effects when aiming at participants with excess weight (that is, overweight or obesity), both for body mass index, waist circumference, waist-to-height ratio, percentage of obesity, and percentage of abdominal obesity. Mediterranean diet-based interventions have a significant effect on reducing the body mass index as well as reducing obesity in children and adolescents (aged 3–18 y). This trial was registered at PROSPERO as CRD42023386789.	en
dc.description.sponsorship	JFL-G is a Margarita Salas Fellow (Universidad Pública de Navarra–1225/2022). AG-H is a Miguel Servet Fellow (Instituto de Salud Carlos III–CP18/0150).	en
dc.format.mimetype	application/pdf	en
dc.format.mimetype	application/zip	en
dc.identifier.citation	López-Gil, J. F., García-Hermoso, A., Sotos-Prieto, M., Cavero-Redondo, I., Martínez-Vizcaíno, V., & Kales, S. N. (2023). Mediterranean diet-based interventions to improve anthropometric and obesity indicators in children and adolescents: A systematic review with meta-analysis of randomized controlled trials. Advances in Nutrition, 14(4), 858-869. https://doi.org/10.1016/j.advnut.2023.04.011	en
dc.identifier.doi	10.1016/j.advnut.2023.04.011
dc.identifier.issn	2161-8313
dc.identifier.uri	https://academica-e.unavarra.es/handle/2454/46555
dc.language.iso	eng	en
dc.publisher	Elsevier	en
dc.relation.ispartof	Advances in Nutrition 14 (2023) 858–869	en
dc.relation.publisherversion	https://doi.org/10.1016/j.advnut.2023.04.011
dc.rights	© 2023 The Authors. This is an open access article under the CC BY license.	en
dc.rights.accessRights	info:eu-repo/semantics/openAccess
dc.rights.uri	https://creativecommons.org/licenses/by/4.0/
dc.subject	Eating healthy	en
dc.subject	Lifestyle	en
dc.subject	Obesity	en
dc.subject	Overweight	en
dc.subject	Preschoolers	en
dc.subject	Young population	en
dc.subject	Youths	en
dc.title	Mediterranean diet-based interventions to improve anthropometric and obesity indicators in children and adolescents: a systematic review with meta-analysis of randomized controlled trials	en
dc.type	info:eu-repo/semantics/article
dc.type.version	info:eu-repo/semantics/publishedVersion
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