Muscular strength as a predictor of all-cause mortality in an apparently healthy population: a systematic review and meta-analysis of data from approximately 2 million men and women
| dc.contributor.author | García Hermoso, Antonio | |
| dc.contributor.author | Cavero-Redondo, Iván | |
| dc.contributor.author | Ramírez Vélez, Robinson | |
| dc.contributor.author | Ruiz, Jonatan R. | |
| dc.contributor.author | Ortega, Francisco B. | |
| dc.contributor.author | Lee, Duck-Chul | |
| dc.contributor.author | Martínez Vizcaíno, Vicente | |
| dc.contributor.department | Ciencias de la Salud | es_ES |
| dc.contributor.department | Osasun Zientziak | eu |
| dc.date.accessioned | 2025-01-07T13:35:46Z | |
| dc.date.available | 2025-01-07T13:35:46Z | |
| dc.date.issued | 2018-09-25 | |
| dc.date.updated | 2025-01-07T13:28:06Z | |
| dc.description.abstract | Objectives: The aims of the present systematic review and meta-analysis were to determine the relationship between muscular strength and all-cause mortality risk and to examine the sex-specific impact of muscular strength on all-cause mortality in an apparently healthy population. Data Sources: Two authors systematically searched MEDLINE, EMBASE and SPORTDiscus databases and conducted manual searching of reference lists of selected articles. Study Selection: Eligible cohort studies were those that examined the association of muscular strength with all-cause mortality in an apparently healthy population. The hazard ratio (HR) estimates with 95% confidence interval (CI) were pooled by using random effects meta-analysis models after assessing heterogeneity across studies. Data Extraction: Two authors independently extracted data. Data Synthesis: Thirty-eight studies with 1,907,580 participants were included in the meta-analysis. The included studies had a total of 63,087 deaths. Higher levels of handgrip strength were associated with a reduced risk of all-cause mortality (HR=0.69; 95% CI, 0.64-0.74) compared with lower muscular strength, with a slightly stronger association in women (HR=0.60; 95% CI, 0.51-0.69) than men (HR=0.69; 95% CI, 0.62-0.77) (all P<.001). Also, adults with higher levels of muscular strength, as assessed by knee extension strength test, had a 14% lower risk of death (HR=0.86: 95% CI, 0.80-0.93; P<.001) compared with adults with lower muscular strength. Conclusions: Higher levels of upper- and lower-body muscular strength are associated with a lower risk of mortality in adult population, regardless of age and follow-up period. Muscular strength tests can be easily performed to identify people with lower muscular strength and, consequently, with an increased risk of mortality. | en |
| dc.description.sponsorship | Funding for A.G.H. was provided by Banco Santander, SA through program "Becas Iberoamérica ca. Jóvenes Profesores Investigadores. Santander Universidades 2016". | |
| dc.format.mimetype | application/pdf | en |
| dc.identifier.citation | García-Hermoso, A., Cavero-Redondo, I., Ramírez-Vélez, R., Ruiz, J. R., Ortega, F. B., Lee, D. C., Martínez-Vizcaíno, V. (2018) Muscular strength as a predictor of all-cause mortality in an apparently healthy population: a systematic review and meta-analysis of data from approximately 2 million men and women. Archives of Physical Medicine and Rehabilitation, 99(10), 2100-2113. https://doi.org/10.1016/j.apmr.2018.01.008. | |
| dc.identifier.doi | 10.1016/j.apmr.2018.01.008 | |
| dc.identifier.issn | 0003-9993 | |
| dc.identifier.uri | https://academica-e.unavarra.es/handle/2454/52825 | |
| dc.language.iso | eng | |
| dc.publisher | Elsevier | |
| dc.relation.ispartof | Archives of Physical Medicine and Rehabilitation, 99(10), 2100-2113 | |
| dc.relation.publisherversion | https://doi.org/10.1016/j.apmr.2018.01.008 | |
| dc.rights | © 2018 by the American Congress of Rehabilitation Medicine. This manuscript version is made available under the CC-BY-NC-ND 4.0. | |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess | |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.subject | Death | en |
| dc.subject | Hand strength | en |
| dc.subject | Leg strength | en |
| dc.subject | Muscles | en |
| dc.title | Muscular strength as a predictor of all-cause mortality in an apparently healthy population: a systematic review and meta-analysis of data from approximately 2 million men and women | en |
| dc.type | info:eu-repo/semantics/article | |
| dc.type.version | info:eu-repo/semantics/acceptedVersion | |
| dspace.entity.type | Publication | |
| relation.isAuthorOfPublication | e84ae68a-fa4a-4e00-be27-bedfffc8612e | |
| relation.isAuthorOfPublication | d0c2c11e-01d0-46ff-93b4-36b11beaf269 | |
| relation.isAuthorOfPublication.latestForDiscovery | e84ae68a-fa4a-4e00-be27-bedfffc8612e |