Cohort Profile: CArdiovascular Risk in patients with DIAbetes in NAvarra (CARDIANA cohort)

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dc.contributor.authorTamayo Rodríguez, Ibai
dc.contributor.authorLibrero, Julián
dc.contributor.authorGalbete Jiménez, Arkaitz
dc.contributor.authorCambra Contin, Koldo
dc.contributor.authorEnguita Germán, Mónica
dc.contributor.authorForga, Lluís
dc.contributor.authorGoñi, María José
dc.contributor.authorLecea, Óscar
dc.contributor.authorGorricho Mendívil, Javier
dc.contributor.authorOlazarán Santesteban, Álvaro
dc.contributor.authorArnedo Ajona, Laura
dc.contributor.authorMoreno Iribas, Conchi
dc.contributor.authorLafita, Javier
dc.contributor.authorIbáñez Beroiz, Berta
dc.contributor.departmentCiencias de la Saludes_ES
dc.contributor.departmentOsasun Zientziakeu
dc.contributor.departmentEstadística, Informática y Matemáticases_ES
dc.contributor.departmentEstatistika, Informatika eta Matematikaeu
dc.contributor.departmentGestión de Empresases_ES
dc.contributor.departmentEnpresen Kudeaketaeu
dc.date.accessioned2023-05-04T06:35:09Z
dc.date.available2023-05-04T06:35:09Z
dc.date.issued2023
dc.date.updated2023-05-04T06:01:34Z
dc.description.abstractPurpose The CArdiovascular Risk in patients with DIAbetes in Navarra (CARDIANA cohort) cohort was established to assess the effects of sociodemographic and clinical variables on the risk of cardiovascular events in patients with type 1 (T1D) or type 2 (T2D) diabetes, with a special focus on socioeconomic factors, and to validate and develop cardiovascular risk models for these patients. Participants The CARDIANA cohort included all patients with T1D and T2D diabetes registered in the Public Health Service of Navarra with prevalent disease on 1 January 2012. It consisted of 1067 patients with T1D (ages 2–88 years) and 33842 patients with T2D (ages 20–105 years), whose data were retrospectively extracted from the Health and Administrative System Databases. Findings to date The follow-up period for wave 1 was from 1 January 2012 to 31 December 2016. During these 5 years, 9 patients (0.8%; 95%CI (0.4% to 1.6%)) in the T1D cohort developed a cardiovascular disease event, whereas for the T2D cohort, 2602 (7.7%; 95%CI (7.4% to 8.0%)) had an event. For the T2D cohort, physical activity was associated with a reduced risk of cardiovascular events, with adjusted estimated ORs equal to 0.84 (95% CI 0.66 to 1.07) for the partially active group and 0.71 (95% CI 0.56 to 0.91) for the active group, compared with patients in the non-active group. Future plans The CARDIANA cohort is currently being used to assess the effect of sociodemographic risk factors on CV risk at 5 years and to externally validate cardiovascular predictive models. A second wave is being conducted in late 2022 and early 2023, to extend the follow-up other 5 years, from 1 January 2016 to 31 December 2021. Periodic data extractions are planned every 5 years.en
dc.description.sponsorshipThis work has received funding from the Instituto de Salud Carlos III through grant PI15/02196 and via the CONCEPT project (grants PI19/00154, PI19/00381). It has also received funding from REDISSEC RD16/0001/0014 and RICAPPS RD21/0016/0016, two Spanish Networks supported by Carlos III Health Institute and the European Regional Development Funding (FEDER).en
dc.format.mimetypeapplication/pdfen
dc.identifier.citationTamayo, I., Librero-Lopez, J., Galbete, A., Cambra, K., Enguita-Germán, M., Forga, L., Goñi, M. J., Lecea, O., Gorricho, J., Olazarán, Á., Arnedo, L., Moreno-Iribas, C., Lafita, J., & Ibañez-Beroiz, B. (2023). Cohort profile: Cardiovascular risk in patients with diabetes in navarra(CARDIANA cohort). BMJ Open, 13(1), e066052. https://doi.org/10.1136/bmjopen-2022-066052en
dc.identifier.doi10.1136/bmjopen-2022-066052
dc.identifier.issn2044-6055
dc.identifier.urihttps://academica-e.unavarra.es/handle/2454/45217
dc.language.isoengen
dc.publisherBMJen
dc.relation.ispartofBMJ Open, 2023; 13(1), 1-8en
dc.relation.projectIDinfo:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PI19%2F00154/ES/
dc.relation.projectIDinfo:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PI19%2F00381/ES/
dc.relation.projectIDinfo:eu-repo/grantAgreement/MINECO//RD16%2F0001%2F0014/ES/
dc.relation.projectIDinfo:eu-repo/grantAgreement///RD21%2F0016%2F0016/
dc.relation.publisherversionhttps://doi.org/10.1136/bmjopen-2022-066052
dc.rights© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY.en
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectCardiac epidemiologyen
dc.subjectGeneral diabetesen
dc.subjectHealth informaticsen
dc.subjectRisk managementen
dc.titleCohort Profile: CArdiovascular Risk in patients with DIAbetes in NAvarra (CARDIANA cohort)en
dc.typeinfo:eu-repo/semantics/article
dc.type.versioninfo:eu-repo/semantics/publishedVersion
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