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Mostrando ítems 11-19 de 19
Operones no-contiguos: una nueva estrategia para coordinar la expresión de genes en bacterias
(2020)
info:eu-repo/semantics/doctoralThesis,
En esta tesis demostramos la existencia de un nivel superior de organización en la estructura del operón que denominamos operón no-contiguo y que consiste en un operón que contiene un gen o genes que se transcriben en la ...
Caracterización del sistema sensorial de dos componentes de Staphylococcus aureus
(2020)
info:eu-repo/semantics/doctoralThesis,
En este trabajo de tesis hemos evaluado dos aproximaciones diferentes dedicadas a la búsqueda de fármacos que tengan como diana de acción los TCSs. Por un lado, dentro del proyecto 'Nuevas estrategias para el control de ...
Novel strategies for treating biofilm and MRSA associated infections
(2021)
info:eu-repo/semantics/doctoralThesis,
En esta tesis hemos trabajado en dos estrategias, un cribado fenotípico y
otro frente a una diana específica, que podrían ayudar a ampliar las alternativas
terapéuticas frente a S. aureus. En el primer capítulo, nos hemos ...
Fitness cost evolution of natural plasmids of staphylococcus aureus
(American Society for Microbiology, 2021)
info:eu-repo/semantics/article,
Plasmids have largely contributed to the spread of antimicrobial resistance genes among Staphylococcus strains. Knowledge about the fitness cost that plasmids confer on clinical staphylococcal isolates and the coevolutionary ...
The role of ArlRS and VraSR in regulating ceftaroline hypersusceptibility in methicillin-resistant Staphylococcus aureus
(MDPI, 2021)
info:eu-repo/semantics/article,
Methicillin-resistant Staphylococcus aureus infections are a global health problem. New control strategies, including fifth-generation cephalosporins such as ceftaroline, have been developed, however rare sporadic resistance ...
Functional specificity and post-transcriptional regulation of the cold shock proteins in Staphylococcus aureus
(2020)
info:eu-repo/semantics/doctoralThesis,
En esta Tesis se han descifrado aspectos relevantes sobre las funciones de las proteínas CSPs de Staphylococcus aureus y su regulación, que pueden ser extrapoladas a otras bacterias. Específicamente, demostramos que sólo ...
Experimental polymorphism survey in intergenic regions of the icaADBCR locus in Staphylococcus aureus isolates from periprosthetic joint infections
(MDPI, 2022)
Artículo / Artikulua,
Staphylococcus aureus is a leading cause of prosthetic joint infections (PJI) characterized
by bacterial biofilm formation and recalcitrance to immune-mediated clearance and antibiotics.
The molecular events behind PJI ...
Systematic reconstruction of the complete two-component sensorial network in staphylococcus aureus
(American Society for Microbiology, 2020)
info:eu-repo/semantics/article,
In bacteria, adaptation to changes in the environment is mainly controlled through two-component signal transduction systems (TCSs). Most bacteria contain dozens of TCSs, each of them responsible for sensing a different ...
The impact of two-component sensorial network in staphylococcal speciation
(Elsevier, 2020)
info:eu-repo/semantics/article,
Bacteria use two-component systems (TCSs) to sense and respond to their environments. Free-living bacteria usually contain dozens of TCSs, each of them responsible for sensing and responding to a different range of signals. ...