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Staphylococcus aureus develops an alternative, ica-independent biofilm in the absence of the arlRS two-component system
(American Society for Microbiology, 2005)
info:eu-repo/semantics/article,
The biofilm formation capacity of Staphylococcus aureus clinical isolates is considered an important virulence
factor for the establishment of chronic infections. Environmental conditions affect the biofilm formation
capacity ...
Sensory deprivation in Staphylococcus aureus
(Springer Nature, 2018)
info:eu-repo/semantics/article,
Bacteria use two-component systems (TCSs) to sense and respond to environmental
changes. The core genome of the major human pathogen Staphylococcus aureus encodes 16
TCSs, one of which (WalRK) is essential. Here we show ...
SarA positively controls Bap-dependent biofilm formation in Staphylococcus aureus
(American Society for Microbiology, 2005)
info:eu-repo/semantics/article,
The biofilm-associated protein Bap is a staphylococcal surface protein involved in biofilm formation. We
investigated the influence of the global regulatory locus sarA on bap expression and Bap-dependent biofilm
formation ...
Staphylococcus aureus susceptibility to complestatin and corbomycin depends on the VraSR two-component system
(American Society for Microbiology, 2023)
Artículo / Artikulua,
The overuse of antibiotics in humans and livestock has driven the emergence and spread of antimicrobial resistance and has therefore prompted research
on the discovery of novel antibiotics. Complestatin (Cm) and corbomycin ...
Inhibiting the two‑component system GraXRS with verteporfin to combat Staphylococcus aureus infections
(Nature Research, 2020)
Artículo / Artikulua,
Infections caused by Staphylococcus aureus pose a serious and sometimes fatal health issue. With the
aim of exploring a novel therapeutic approach, we chose GraXRS, a Two-Component System (TCS)
that determines bacterial ...
Relevant role of fibronectin-binding proteins in Staphylococcus aureus biofilm-associated foreign-body infections
(American Society for Microbiology, 2009)
info:eu-repo/semantics/article,
Staphylococcus aureus can establish chronic infections on implanted medical devices due to its capacity to form biofilms. Analysis of the factors that assemble cells into a biofilm has revealed the occurrence of strains ...
Role of biofilm-associated protein bap in the pathogenesis of bovine Staphylococcus aureus
(American Society for Microbiology, 2004)
info:eu-repo/semantics/article,
Staphylococcus aureus is a common cause of intramammary infections, which frequently become chronic, associated with the ability of the bacteria to produce biofilm. Here, we report a relationship between the ability to ...
Expression of the biofilm-associated protein interferes with host protein receptors of Staphylococcus aureus and alters the infective process
(American Society for Microbiology, 2002)
info:eu-repo/semantics/article,
The adherence of Staphylococcus aureus to soluble proteins and extracellular-matrix components of the host is one of the key steps in the pathogenesis of staphylococcal infections. S. aureus presents a family of adhesins ...
Protein A-mediated multicellular behavior in Staphylococcus aureus
(American Society for Microbiology, 2008)
info:eu-repo/semantics/article,
The capacity of Staphylococcus aureus to form biofilms on host tissues and implanted medical devices is one of the major virulence traits underlying persistent and chronic infections. The matrix in which S. aureus cells ...
Calcium inhibits bap-dependent multicellular behavior in Staphylococcus aureus
(American Society for Microbiology, 2004)
info:eu-repo/semantics/article,
Bap (biofilm-associated protein) is a 254-kDa staphylococcal surface protein implicated in formation of biofilms by staphylococci isolated from chronic mastitis infections. The presence of potential EF-hand motifs in the ...