Malnutrition and poor physical function are associated with higher comorbidity index in hospitalized older adults
Fecha
2022Autor
Versión
Acceso abierto / Sarbide irekia
Tipo
Artículo / Artikulua
Versión
Versión publicada / Argitaratu den bertsioa
Impacto
|
10.3389/fnut.2022.920485
Resumen
Background: The Charlson Comorbidity Index (CCI) is the most widely used method
to measure comorbidity and predict mortality. There is no evidence whether malnutrition
and/or poor physical function are associated with higher CCI in hospitalized patients.
Therefore, this study aimed to (i) analyze the association between the CCI with nutritional
status and with physical function of hospitalize ...
[++]
Background: The Charlson Comorbidity Index (CCI) is the most widely used method
to measure comorbidity and predict mortality. There is no evidence whether malnutrition
and/or poor physical function are associated with higher CCI in hospitalized patients.
Therefore, this study aimed to (i) analyze the association between the CCI with nutritional
status and with physical function of hospitalized older adults and (ii) examine the individual
and combined associations of nutritional status and physical function of older inpatients
with comorbidity risk.
Methods: A total of 597 hospitalized older adults (84.3 ± 6.8 years, 50.3% women)
were assessed for CCI, nutritional status (the Mini Nutritional Assessment-Short Form
[MNA-SF]), and physical function (handgrip strength and the Short Physical Performance
Battery [SPPB]).
Results: Better nutritional status (p < 0.05) and performance with handgrip strength
and the SPPB were significantly associated with lower CCI scores among both men
(p < 0.005) and women (p < 0.001). Patients with malnutrition or risk of malnutrition
(OR: 2.165, 95% CI: 1.408–3.331, p < 0.001) as well as frailty (OR: 3.918, 95% CI:
2.326–6.600, p < 0.001) had significantly increased the risk for being at severe risk
of comorbidity. Patients at risk of malnutrition or that are malnourished had higher
CCI scores regardless of being fit or unfit according to handgrip strength (p for trend
<0.05), and patients classified as frail had higher CCI despite their nutritional status (p
for trend <0.001).
Conclusions: The current study reinforces the use of the MNA-SF and the SPPB in
geriatric hospital patients as they might help to predict poor clinical outcomes and thus
indirectly predict post-discharge mortality risk. [--]
Materias
Chronic diseases,
Geriatrics,
Inpatients,
Mortality,
Muscle strength,
Nutritional status
Editor
Frontiers Media
Publicado en
Frontiers in Nutrition 2022, 9 (920485)
Departamento
Universidad Pública de Navarra/Nafarroako Unibertsitate Publikoa. Institute on Innovation and Sustainable Development in Food Chain - ISFOOD
Versión del editor
Entidades Financiadoras
This study was supported by the Basque Government (2016111138). MA was supported by a grant from the University of the Basque Country (PIF17/186) and IE was supported by a grant from the University of the Basque Country in collaboration with the University of Bordeaux (UBX) (PIFBUR16/07).
Aparece en las colecciones
Los documentos de Academica-e están protegidos por derechos de autor con todos los derechos reservados, a no ser que se indique lo contrario.
La licencia del ítem se describe como © 2022 Amasene, Medrano, Echeverria, Urquiza, Rodriguez-Larrad,
Diez, Labayen and Ariadna. This is an open-access article distributed under the
terms of the Creative Commons Attribution License (CC BY). The use, distribution
or reproduction in other forums is permitted, provided the original author(s) and
the copyright owner(s) are credited and that the original publication in this journal
is cited, in accordance with accepted academic practice. No use, distribution or
reproduction is permitted which does not comply with these terms.