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Phenolic profile and biological activities of the pepino (solanum muricatum) fruit and itswild relative S. caripense
dc.creator | Herraiz, Francisco J. | es_ES |
dc.creator | Villaño Valencia, Débora | es_ES |
dc.creator | Plazas, Mariola | es_ES |
dc.creator | Vilanova, Santiago | es_ES |
dc.creator | Ferreres, Federico | es_ES |
dc.creator | Prohens, Jaime | es_ES |
dc.creator | Moreno Fernández, Diego Ángel | es_ES |
dc.date.accessioned | 2024-03-22T11:57:44Z | |
dc.date.available | 2024-03-22T11:57:44Z | |
dc.date.issued | 2016 | |
dc.identifier.citation | Herraiz, F. J., Villaño, D., Plazas, M., Vilanova, S., Ferreres, F., Prohens, J., Moreno, D. A. (2016) Phenolic profile and biological activities of the pepino (solanum muricatum) fruit and itswild relative s. caripense. International journal of molecular sciences, 17(3), 1-15. https://doi.org/10.3390/ijms17030394. | es_ES |
dc.identifier.issn | 1661-6596 | |
dc.identifier.uri | https://hdl.handle.net/2454/47763 | |
dc.description.abstract | The pepino (Solanum muricatum) is an edible and juicy fruit native to the Andean region which is becoming increasingly important. However, little information is available on its phenolic composition and bioactive properties. Four pepino varieties (37-A, El Camino, Puzol, and Valencia) and one accession (E-7) of its close wild relative S. caripense were characterized by HPLC-DAD-MSn/ESI. Twenty-four hydroxycinnamic acid derivatives were detected (5 to 16 compounds per variety or accession), with differences of more than two-fold for their total content among the materials studied. The major phenolics in the pepino varieties were chlorogenic acids and derivatives, while in S. caripense a caffeoyl-synapoyl-quinic acid was the major compound. The in vitro antioxidant capacity (DPPH (2,2-diphenyl-1-picrylhydrazyl hydrate), ORAC (oxygen radical absorbance capacity), and TRC (total reducing capacity) tests) was higher in S. caripense. Pepino and S. caripense extracts were not toxic for RAW 264.7 macrophage cells, and the raw extracts inhibitedNOproduction of the lipopolysaccharide (LPS)-stimulated macrophages by 36% (El Camino) to 67% (37-A). No single variety ranked high simultaneously for hydroxycinnamic acids content, antioxidant activity and biological activity. We suggest the screening of large collections of germplasm or the use of complementary crosses between Puzol (high for hydroxycinnamic acids and biological activity) and S. caripense E-7 (high for antioxidant activity) to select and breed pepino varieties with enhanced properties. | en |
dc.description.sponsorship | The authors express their gratitude to the Spanish Ministry of Economy and Competitiveness (MINECO) and the Iberian-American Program for Cooperation and Development (CYTED) (Ref. 112RT0460) - CORNUCOPIA Thematic Network (URL: redcornucopia.org). | en |
dc.format.mimetype | application/pdf | en |
dc.language.iso | eng | en |
dc.publisher | MDPI | en |
dc.relation.ispartof | International journal of molecular sciences (2016), vol. 17, núm. 3 | es_ES |
dc.rights | © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license. | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.subject | Antioxidants | es_ES |
dc.subject | Biological activity | es_ES |
dc.subject | HPLC-DAD-MSn/ESI | es_ES |
dc.subject | Macrophages | es_ES |
dc.title | Phenolic profile and biological activities of the pepino (solanum muricatum) fruit and itswild relative S. caripense | en |
dc.type | Artículo / Artikulua | es |
dc.type | info:eu-repo/semantics/article | en |
dc.date.updated | 2024-03-22T11:48:09Z | |
dc.contributor.department | Agronomía, Biotecnología y Alimentación | es_ES |
dc.contributor.department | Agronomia, Bioteknologia eta Elikadura | eu |
dc.contributor.department | Institute on Innovation and Sustainable Development in Food Chain - ISFOOD | en |
dc.rights.accessRights | Acceso abierto / Sarbide irekia | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | en |
dc.identifier.doi | 10.3390/ijms17030394 | |
dc.relation.projectID | info:eu-repo/grantAgreement/MINECO//112RT0460 | |
dc.relation.publisherversion | https://doi.org/10.3390/ijms17030394 | |
dc.type.version | Versión publicada / Argitaratu den bertsioa | es |
dc.type.version | info:eu-repo/semantics/publishedVersion | en |