Listar Dpto. Ciencias de la Salud - Osasun Zientziak Saila por título
Mostrando ítems 998-1017 de 1083
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Tackling the biological meaning of the human olfactory bulb dyshomeostatic proteome across neurological disorders: an integrative bioinformatic approach
Olfactory dysfunction is considered an early prodromal marker of many neurodegenerative diseases. Neuropathological changes and aberrant protein aggregates occur in the olfactory bulb (OB), triggering a tangled cascade of ... -
Tailored prevention of functional decline through a multicomponent exercise program in hospitalized oncogeriatric patients: study protocol for a randomized clinical trial
BACKGROUND: Cancer mostly affects older adults, causing a wide variety of diagnostic and therapeutic dilemmas. One of the most important moments in cancer patients is the hospitalization period, in which older patients ... -
Targeting fatty acid-binding protein 4 improves pathologic features of aortic stenosis
Aortic stenosis (AS) is a fibrocalcific disease of the aortic valves (AVs). Sex-differences in AS pathophysiology have recently been described. High levels of fatty acid-binding protein 4 (FAPB4) in atherosclerotic plaques ... -
Targeting key players of neuroendocrine differentiation in prostate cancer
Neuroendocrine prostate cancer (NEPC) is a highly aggressive subtype of prostate cancer (PC) that commonly emerges through a transdifferentiation process from prostate adenocarcinoma and evades conventional therapies. ... -
Task failure during exercise to exhaustion in normoxia and hypoxia is due to reduced muscle activation caused by central mechanisms while muscle metaboreflex does not limit performance
To determine whether task failure during incremental exercise to exhaustion (IE) is principally due to reduced neural drive and increased metaboreflex activation eleven men (22 ± 2 years) performed a 10 s control isokinetic ... -
La técnica de Nyhus en la reparación de las hernias inguinales recidivadas: análisis de una serie de 203 pacientes
Introducción y objetivo: la elección de una técnica para el tratamiento de las hernias inguinocrurales recidivadas resulta controvertida por la variabilidad de abordajes y opciones técnicas. Presentamos los casos de hernia ... -
Telomere length correlates with subtelomeric DNA methylation in long-term mindfulness practitioners
Mindfulness and meditation techniques have proven successful for the reduction of stress and improvement in general health. In addition, meditation is linked to longevity and longer telomere length, a proposed biomarker ... -
Tendances internationales de la mortalité maternelle et infantile en Afrique de 1990-2016
Objectif général: savoir la tendance annuelle de réduction du taux de mortalité maternelle et infantile entre 1990 à 2015 et 2016 respectivement. Objectifs spécifiques: savoir les tendances annuelles de réduction de la ... -
Tendencias en la mortalidad y morbilidad por enfermedad de Alzheimer en la Unión Europea
El objetivo de esta tesis es analizar las tendencias de mortalidad y morbilidad hospitalaria de la enfermedad de Alzheimer en los países de la Unión Europea en el periodo 2002-2012, a través del análisis de los datos y el ... -
Tendencias temporales de suicidio en niños, adolescentes y jóvenes
Navarra dispone desde 2014 de un protocolo de colaboración interinstitucional para la prevención y actuación ante conductas suicidas. El documento fue pionero ya que adopta un punto de vista interdepartamental, y parte de ... -
Tendencias temporales de suicidio en niños, adolescentes y jóvenes
El suicidio a cualquier edad es un potente indicador de salud pública y nos sitúa ante un hecho humano de gran complejidad. Los años de vida perdidos, el impacto traumático que genera en los supervivientes más directos y ... -
Teoría de la mente en los subtipos del trastorno por déficit de atención e hiperactividad
Introducción: el Trastorno por Déficit de Atención e Hiperactividad (TDAH) es el trastorno del neurodesarrollo más frecuente en la infancia con una prevalencia estimada de entre un 3% y un 8%. Sus consecuencias más apreciables ... -
Terapia sistémica breve en personas expuestas a un evento altamente estresante reciente: Un ensayo controlado aleatorizado
Antecedentes: Los eventos altamente estresantes pueden tener efectos nocivos en el bienestar y salud mental en las personas. Objetivo: Evaluar la eficacia de un protocolo de intervención preventiva basado en la ... -
A themed game to learn about nursing theories and models: a descriptive study
One of the most demanding challenges for teachers in undergraduate nursing programmes is teaching the intangible aspects of the discipline, such as its conceptual and theoretical bases. This study aimed to evaluate nursing ... -
Theory based capacity building intervention for intersectoral action for health at local governments: an exploratory pilot study
Aim: To design, implement and evaluate a nurse- led capacity building intervention (PromoGOB) for intersectoral action for health at local governments. Design: The programme was based on theories of the policy process and ... -
Thermal characterization, polymorphism, and stability evaluation of Se-NSAID derivatives with potent anticancer activity
Stability, thermal characterization, and identification of possible polymorphism are relevant in the development of novel therapeutic drugs. In this context, thirty new nonsteroidal anti-inflammatory drug (NSAID) derivatives ... -
Time trends and inequalities of physical activity domains and sitting time in South America
Background: we aimed to investigate time trends and inequalities of different physical activity (PA) domains and sitting time (ST) in adults from South American countries. Methods: we included cross-sectional data of ... -
Time-restricted eating and supervised exercise for improving hepatic steatosis and cardiometabolic health in adults with obesity: protocol for the TEMPUS randomised controlled trial
Introduction. Metabolic dysfunction-associated steatotic liver disease is a major public health problem considering its high prevalence and its strong association with extrahepatic diseases. Implementing strategies based ... -
TNF-α-secreting tumor-infiltrated monocytes play a pivotal role during anti-PD-L1 immunotherapy
Immune checkpoint blockade (ICB) of the PD-1 pathway revolutionized the survival forecast for advanced non-small cell lung cancer (NSCLC). Yet, the majority of PD-L1+ NSCLC patients are refractory to anti-PD-L1 therapy. ... -
Top 10 international priorities for physical fitness research and surveillance among children and adolescents: a twin-panel Delphi study
Background The measurement of physical ftness has a history that dates back nearly 200 years. Recently, there has been an increase in international research and surveillance on physical ftness creating a need for setting ...