Tailored prevention of functional decline through a multicomponent exercise program in hospitalized oncogeriatric patients: study protocol for a randomized clinical trial
Fecha
2023Autor
Versión
Acceso abierto / Sarbide irekia
Tipo
Artículo / Artikulua
Versión
Versión publicada / Argitaratu den bertsioa
Impacto
|
10.1007/s12603-023-1977-y
Resumen
BACKGROUND: Cancer mostly affects older adults, causing a wide
variety of diagnostic and therapeutic dilemmas. One of the most
important moments in cancer patients is the hospitalization period, in
which older patients usually remain bedridden for many hours and this
may lead to the appearance of sarcopenia and disability.
METHODS: We present the research protocol for a randomized
controlle ...
[++]
BACKGROUND: Cancer mostly affects older adults, causing a wide
variety of diagnostic and therapeutic dilemmas. One of the most
important moments in cancer patients is the hospitalization period, in
which older patients usually remain bedridden for many hours and this
may lead to the appearance of sarcopenia and disability.
METHODS: We present the research protocol for a randomized
controlled trial that will analyze whether an intervention applied to
older patients (≥ 65 years) who are hospitalized for acute medical
conditions in an Oncology Department improves function. A total
of 240 hospitalized older patients will be recruited in the Hospital
Universitario de Navarra, Pamplona, Spain, and they will be
randomized. The intervention consists of a multicomponent exercise
training program that will take place for 4 consecutive days (2
sessions/day). The control group will receive usual hospital care,
which will include physical rehabilitation when needed. The primary
end point will be the change in functional capacity from baseline to
hospital discharge, assessed with the Short Physical Performance
Battery (SPPB). Secondary end points will be changes in cognitive and
mood status, quality of life, fatigue, strength (dynamic and handgrip),
pain, nutrition, length of stay, falls, readmission rate and mortality at 3
months after discharge.
RESULTS: Basal data of the patients included in the RCT are
described. The foreseen recruitment will not be achieved due to
the context of the Covid pandemic and the significantly different
responses observed during the clinical trial in oncogeriatric patients
compared to our previous experience in older adults hospitalized for
medical reasons.
DISCUSSION: If our hypothesis is correct and shows that a
multicomponent, individualized and progressive exercise program is
an effective therapy for improving the capacity of acutely hospitalized
older patients compared to usual care, a change in the current system
of hospitalization may be justified in oncogeriatric patients. [--]
Materias
Cancer,
Disability,
Functional capacity,
Hospitalization,
Multicomponent exercise,
Oncogeriatric
Editor
Elsevier
Publicado en
Journal of Nutrition, Health and Aging 27(10), 2023, 911-918
Departamento
Universidad Pública de Navarra. Departamento de Ciencias de la Salud /
Nafarroako Unibertsitate Publikoa. Osasun Zientziak Saila /
Universidad Pública de Navarra. Departamento de Estadística, Informática y Matemáticas /
Nafarroako Unibertsitate Publikoa. Estatistika, Informatika eta Matematika Saila
Versión del editor
Entidades Financiadoras
Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature.
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