Intra-assessment resting metabolic rate variability is associated with cardiometabolic risk factors in middle-aged adults

Alcántara Alcántara, Juan Manuel; Osuna Prieto, Francisco J.; Castillo, Manuel J.; Plaza Florido, Abel; Amaro Gahete, Francisco J.

Intra-assessment resting metabolic rate variability is associated with cardiometabolic risk factors in middle-aged adults

dc.contributor.author	Alcántara Alcántara, Juan Manuel
dc.contributor.author	Osuna Prieto, Francisco J.
dc.contributor.author	Castillo, Manuel J.
dc.contributor.author	Plaza Florido, Abel
dc.contributor.author	Amaro Gahete, Francisco J.
dc.contributor.department	Ciencias de la Salud	es_ES
dc.contributor.department	Osasun Zientziak	eu
dc.contributor.department	Institute on Innovation and Sustainable Development in Food Chain - ISFOOD	en
dc.date.accessioned	2024-04-25T18:57:01Z
dc.date.available	2024-04-25T18:57:01Z
dc.date.issued	2023
dc.date.updated	2024-04-25T18:41:55Z
dc.description.abstract	The intra-assessment resting metabolic rate variability is related to cardiometabolic health, as suggested by previous literature. We studied whether that variability (expressed as coefficient of variation [CV; %]) for oxygen consumption (VO2), carbon dioxide production (VCO2), respiratory exchange ratio (RER), and resting energy expenditure (REE) is similar between men and women, and if is similarly associated with cardiometabolic risk factors. Gas exchange in 72 middle-aged adults was measured by indirect calorimetry. Anthropometrics and body composition, cardiorespiratory fitness, circulating cardiometabolic risk factors, and heart rhythm parameters were also determined. Men and women presented similar intra-assessment resting metabolic rate variability (all p > 0.05). Notably, in men, CV for RER was positively associated with BMI and adiposity (both standardized β = 0.35, Ps ≤ 0.048), while CVs for VO2, VCO2, and REE were negatively associated (standardized β ranged from −0.37 to −0.46, all p ≤ 0.036) with cardiometabolic risk factors. In women, CVs for VCO2 and REE were negatively associated with adiposity (both standardized β = −0.36, Ps ≤ 0.041) and cardiometabolic risk Z-score (standardized β = −0.40 and −0.38, respectively, Ps ≤ 0.05). In conclusion, intra-assessment resting metabolic rate variability could be considered an indicator of cardiometabolic health in middle-aged adults.	en
dc.description.sponsorship	This research was funded by the Spanish Ministry of Education (FPU14/04172), the University of Granada UGR Research and Knowledge Transfer Fund (PPIT) 2016 (Excellence Actions Programme. Units of Scientific Excellence: Scientific Unit of Excellence on Exercise and Health [UCEES]), the Regional Government of Andalusia, Regional Ministry of Economy, Knowledge, Enterprises and University, the European Regional Development Fund (ERDF), ref. SOMM17/6107/UGR, and Redes Temáticas de Investigación Cooperativa RETIC grant Red SAMID RD16/0022. J.M.A.A. is supported by the Juan de la Cierva-Formación Grant FJC2020-044453-I funded by MCIN/AEI/10.13039/501100011033 and “European Union NextGenerationEU/PRTR”. F.J.O.P. is supported by the Margarita Salas postdoctoral research contract program (Ministry of Universities of Spain, European Union—NextGenerationEU). A.P.F. is supported in part by PERC Systems Biology Fund.	en
dc.format.mimetype	application/pdf	en
dc.identifier.citation	Alcantara, J. M. A., Osuna-Prieto, F. J., Castillo, M. J., Plaza-Florido, A., Amaro-Gahete, F. J. (2023) Intra-assessment resting metabolic rate variability is associated with cardiometabolic risk factors in middle-aged adults. Journal of Clinical Medicine, 12(23), 1-14. https://doi.org/10.3390/jcm12237321.	en
dc.identifier.doi	10.3390/jcm12237321
dc.identifier.issn	2077-0383
dc.identifier.uri	https://academica-e.unavarra.es/handle/2454/48038
dc.language.iso	eng	en
dc.publisher	MDPI	en
dc.relation.ispartof	Journal of Clinical Medicine 2023, 12(23), 7321	en
dc.relation.projectID	info:eu-repo/grantAgreement/MECD//FPU14%2F04172/ES/
dc.relation.publisherversion	https://doi.org/10.3390/jcm12237321
dc.rights	© 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license .	en
dc.rights.accessRights	info:eu-repo/semantics/openAccess
dc.rights.uri	https://creativecommons.org/licenses/by/4.0/
dc.subject	Cardiometabolic risk factors	en
dc.subject	Cardiovascular diseases	en
dc.subject	CPX Ultima CardiO2	en
dc.subject	Health status	en
dc.subject	IC	en
dc.subject	Sexual dimorphism	en
dc.title	Intra-assessment resting metabolic rate variability is associated with cardiometabolic risk factors in middle-aged adults	en
dc.type	info:eu-repo/semantics/article
dc.type.version	info:eu-repo/semantics/publishedVersion
dspace.entity.type	Publication
relation.isAuthorOfPublication	81010fc5-9a1b-44dd-8cfe-933acda93159
relation.isAuthorOfPublication.latestForDiscovery	81010fc5-9a1b-44dd-8cfe-933acda93159