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Base pairing interaction between 5′- and 3′-UTRs controls icaR mRNA translation in Staphylococcus aureus
(Public Library of Science, 2013)
Artículo / Artikulua,
The presence of regulatory sequences in the 39 untranslated region (39-UTR) of eukaryotic mRNAs controlling RNA stability
and translation efficiency is widely recognized. In contrast, the relevance of 39-UTRs in bacterial ...
Bap, a biofilm matrix protein of Staphylococcus aureus prevents cellular internalization through binding to GP96 host receptor
(Public Library of Science, 2012)
Artículo / Artikulua,
The biofilm matrix, composed of exopolysaccharides, proteins, nucleic acids and lipids, plays a well-known role as a defence
structure, protecting bacteria from the host immune system and antimicrobial therapy. However, ...
Bacterial biofilm functionalization through Bap amyloid engineering
(Springer Nature, 2022)
Artículo / Artikulua,
Biofilm engineering has emerged as a controllable way to fabricate living structures with programmable functionalities. The amyloidogenic proteins comprising the biofilms can be engineered to create self-assembling ...
Sensory deprivation in Staphylococcus aureus
(Springer Nature, 2018)
info:eu-repo/semantics/article,
Bacteria use two-component systems (TCSs) to sense and respond to environmental
changes. The core genome of the major human pathogen Staphylococcus aureus encodes 16
TCSs, one of which (WalRK) is essential. Here we show ...
Antibiofilm activity of flavonoids on staphylococcal biofilms through targeting BAP amyloids
(Nature Research, 2020)
info:eu-repo/semantics/article,
The opportunistic pathogen Staphylococcus aureus is responsible for causing infections related to indwelling medical devices, where this pathogen is able to attach and form biofilms. The intrinsic properties given by the ...
Near-infrared fluorescence imaging as an alternative to bioluminescent bacteria to monitor biomaterial-associated infections
(Elsevier, 2014)
info:eu-repo/semantics/article,
Biomaterial-associated infection is one of the most common complications related with the
implantation of any biomedical device. Several in vivo imaging platforms have emerged as
powerful diagnostic tools to longitudinally ...
Relevant role of fibronectin-binding proteins in Staphylococcus aureus biofilm-associated foreign-body infections
(American Society for Microbiology, 2009)
info:eu-repo/semantics/article,
Staphylococcus aureus can establish chronic infections on implanted medical devices due to its capacity to form biofilms. Analysis of the factors that assemble cells into a biofilm has revealed the occurrence of strains ...
Protein A-mediated multicellular behavior in Staphylococcus aureus
(American Society for Microbiology, 2008)
info:eu-repo/semantics/article,
The capacity of Staphylococcus aureus to form biofilms on host tissues and implanted medical devices is one of the major virulence traits underlying persistent and chronic infections. The matrix in which S. aureus cells ...
Bap, a Staphylococcus aureus surface protein involved in biofilm formation
(American Society for Microbiology, 2001)
info:eu-repo/semantics/article,
Identification of new genes involved in biofilm formation is needed to understand the molecular basis of strain variation and the pathogenic mechanisms implicated in chronic staphylococcal infections. A biofilm-producing ...
Staphylococcal Bap proteins build amyloid scaffold biofilm matrices in response to environmental signals
(Public Library of Science, 2016)
Artículo / Artikulua,
Major components of the biofilm matrix scaffold are proteins that assemble to create a unified structure that maintain bacteria attached to each other and to surfaces. We provide evidence that a surface protein present in ...