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RinA controls phage-mediated packaging and transfer of virulence genes in gram-positive bacteria
(Oxford University Press, 2011)
Artículo / Artikulua,
Phage-mediated transfer of microbial genetic elements plays a crucial role in bacterial life style and evolution. In this study, we identify the RinA family of phage-encoded proteins as activators required for transcription ...
A super-family of transcriptional activators regulates bacteriophage packaging and lysis in Gram-positive bacteria
(Oxford University Press, 2013)
info:eu-repo/semantics/article,
The propagation of bacteriophages and other mobile genetic elements requires exploitation of the phage mechanisms involved in virion assembly and DNA packaging. Here, we identified and characterized four different families ...
Sensory deprivation in Staphylococcus aureus
(Springer Nature, 2018)
info:eu-repo/semantics/article,
Bacteria use two-component systems (TCSs) to sense and respond to environmental
changes. The core genome of the major human pathogen Staphylococcus aureus encodes 16
TCSs, one of which (WalRK) is essential. Here we show ...
The enterococcal surface protein, Esp, is involved in Enterococcus faecalis biofilm formation
(American Society for Microbiology, 2001)
info:eu-repo/semantics/article,
The enterococcal surface protein, Esp, is a high-molecular-weight surface protein of unknown function whose
frequency is significantly increased among infection-derived Enterococcus faecalis isolates. In this work, a ...
Moonlighting bacteriophage proteins derepress staphylococcal pathogenicity islands
(Nature Research, 2010)
info:eu-repo/semantics/article,
Staphylococcal superantigen-carrying pathogenicity islands (SaPIs) are discrete, chromosomally integrated units of ∼15 kilobases that are induced by helper phages to excise and replicate. SaPI DNA is then efficiently ...
Bap, a biofilm matrix protein of Staphylococcus aureus prevents cellular internalization through binding to GP96 host receptor
(Public Library of Science, 2012)
Artículo / Artikulua,
The biofilm matrix, composed of exopolysaccharides, proteins, nucleic acids and lipids, plays a well-known role as a defence
structure, protecting bacteria from the host immune system and antimicrobial therapy. However, ...
Staphylococcal Bap proteins build amyloid scaffold biofilm matrices in response to environmental signals
(Public Library of Science, 2016)
Artículo / Artikulua,
Major components of the biofilm matrix scaffold are proteins that assemble to create a unified structure that maintain bacteria attached to each other and to surfaces. We provide evidence that a surface protein present in ...
Genome-wide antisense transcription drives mRNA processing in bacteria
(National Academy of Sciences, 2011)
Artículo / Artikulua,
RNA deep sequencing technologies are revealing unexpected levels of complexity in bacterial transcriptomes with the discovery of abundant noncoding RNAs, antisense RNAs, long 5′ and 3′ untranslated regions, and alternative ...
Relevant role of fibronectin-binding proteins in Staphylococcus aureus biofilm-associated foreign-body infections
(American Society for Microbiology, 2009)
info:eu-repo/semantics/article,
Staphylococcus aureus can establish chronic infections on implanted medical devices due to its capacity to form biofilms. Analysis of the factors that assemble cells into a biofilm has revealed the occurrence of strains ...
Role of biofilm-associated protein bap in the pathogenesis of bovine Staphylococcus aureus
(American Society for Microbiology, 2004)
info:eu-repo/semantics/article,
Staphylococcus aureus is a common cause of intramammary infections, which frequently become chronic, associated with the ability of the bacteria to produce biofilm. Here, we report a relationship between the ability to ...