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Mutants in the lipopolysaccharide of Brucella ovis are attenuated and protect against B. ovis infection in mice
(BioMed Central, 2014)
info:eu-repo/semantics/article,
Brucella spp. are Gram-negative bacteria that behave as facultative intracellular parasites of a variety of mammals. This genus includes smooth (S) and rough (R) species that carry S and R lipopolysaccharides (LPS), ...
Brucella abortus ornithine lipids are dispensable outer membrane components devoid of a marked pathogen-associated molecular pattern
(Public Library of Science, 2011)
Artículo / Artikulua,
The brucellae are alpha-Proteobacteria facultative intracellular parasites that cause an important zoonosis. These bacteria escape early detection by innate immunity, an ability associated to the absence of marked ...
What have we learned from brucellosis in the mouse model?
(BioMed Central, 2012)
Artículo / Artikulua,
Brucellosis is a zoonosis caused by Brucella species. Brucellosis research in natural hosts is often precluded by practical, economical and ethical reasons and mice are widely used. However, mice are not natural Brucella ...
The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition
(Public Library of Science, 2012)
Artículo / Artikulua,
Innate immunity recognizes bacterial molecules bearing pathogen-associated molecular patterns to launch inflammatory responses leading to the activation of adaptive immunity. However, the lipopolysaccharide (LPS) of the ...
The extradomain a of fibronectin enhances the efficacy of lipopolysaccharide defective Salmonella bacterins as vaccines in mice
(BioMed Central, 2012)
Artículo / Artikulua,
The Extradomain A from fibronectin (EDA) has an immunomodulatory role as fusion protein with viral and tumor antigens, but its effect when administered with bacteria has not been assessed. Here, we investigated the adjuvant ...
Deletion of the GI-2 integrase and the wbkA flanking transposase improves the stability of Brucella melitensis Rev 1 vaccine
(BioMed Central, 2013)
Artículo / Artikulua,
Brucella melitensis Rev 1 is the best vaccine available for the prophylaxis of small ruminant brucellosis and, indirectly, for reducing human brucellosis. However, Rev 1 shows anomalously high rates of spontaneous dissociation ...
Simultaneous infections by different Salmonella strains in mesenteric lymph nodes of finishing pigs
(BioMed Central, 2014)
Artículo / Artikulua,
Background: Salmonellosis is a major worldwide zoonosis, and Salmonella-infected finishing pigs are considered
one of the major sources of human infections in developed countries. Baseline studies on salmonellosis ...
Identification of lptA, lpxE, and lpxO, three genes involved in the remodeling of Brucella cell envelope
(Frontiers Media, 2018)
info:eu-repo/semantics/article,
The brucellae are facultative intracellular bacteria that cause a worldwide extended zoonosis. One of the pathogenicity mechanisms of these bacteria is their ability to avoid rapid recognition by innate immunity because ...
Sensitivity of the ISO 6579:2002/Amd 1:2007 standard method for detection of Salmonella spp. on mesenteric lymph nodes from slaughter pigs
(American Society for Microbiology, 2012)
info:eu-repo/semantics/article,
The ISO 6579:2002/Amd 1:2007 (ISO) standard has been the bacteriological standard method used in the European Union for
the detection of Salmonella spp. in pig mesenteric lymph nodes (MLN), but there are no published ...
Development of a selective culture medium for primary isolation of the main Brucella species
(American Society for Microbiology, 2011)
info:eu-repo/semantics/article,
Bacteriological diagnosis of brucellosis is performed by culturing animal samples directly on both Farrell
medium (FM) and modified Thayer-Martin medium (mTM). However, despite inhibiting most contaminating
microorganisms, ...