Lossy mode resonance enabling ultra-low detection limit for fibre-optic biosensors (INVITED)

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dc.contributor.authorChiavaioli, Francesco
dc.contributor.authorGiannetti, Ambra
dc.contributor.authorTombelli, Sara
dc.contributor.authorTrono, Cosimo
dc.contributor.authorDel Villar, Ignacio
dc.contributor.authorMatías Maestro, Ignacio
dc.contributor.authorZubiate Orzanco, Pablo
dc.contributor.authorRuiz Zamarreño, Carlos
dc.contributor.authorArregui San Martín, Francisco Javier
dc.contributor.authorBaldini, Francesco
dc.contributor.departmentIngeniaritza Elektrikoa, Elektronikoaren eta Telekomunikazio Ingeniaritzareneu
dc.contributor.departmentInstitute of Smart Cities - ISCen
dc.contributor.departmentIngeniería Eléctrica, Electrónica y de Comunicaciónes_ES
dc.contributor.funderGobierno de Navarra / Nafarroako Gobernua, 72/2015es
dc.date.accessioned2022-02-09T12:50:40Z
dc.date.available2022-02-22T00:00:14Z
dc.date.issued2020
dc.description.abstractThe combination of optical fibre-based biosensors with nanotechnologies is providing the opportunity for the development of in situ, portable, lightweight, versatile and high-sensitivity optical sensing platforms. We report on the generation of lossy mode resonances (LMRs) by means of the deposition of nm-thick SnO2 film on optical fibres. This allows measuring precisely and accurately the changes in refractive index of the fibre-surrounding medium with very high sensitivity compared to other optical technology platforms, such as long period grating or surface plasmon resonance. This approach, mixed with the use of specialty fiber structures such as Dshaped fibres, allows improving the light-matter interaction in strong way. Different imaging systems, i.e. SEM and TEM along with X-EDS tool, have been used to study the optical features of the fiber coating. The shift of the LMR has been monitored in real-time thanks to conventional wavelength interrogation system and ad hoc developed microfluidics. A big leap in performance has been attained by detecting femtomolar concentrations in human serum. The biosensor reusability has been also tested by using a solution of sodium dodecyl sulphate.en
dc.description.sponsorshipThis work was supported by the National Research Council of Italy (CNR) for the Short Term Mobility program 2017, by the Government of Navarra (project no. 72/2015) and by the Spanish Agencia Estatal de Investigacion (AEI) and European Regional Development Fund (FEDER) (TEC2016-78047-R,TEC2016-79367-C2-2-R).en
dc.embargo.lift2022-02-22
dc.embargo.terms2022-02-22
dc.format.extent6 p.
dc.format.mimetypeapplication/pdfen
dc.identifier.doi10.1007/978-3-030-37558-4_49
dc.identifier.isbn978-3-030-37558-4; 978-3-030-37557-7
dc.identifier.issn1876-1119
dc.identifier.urihttps://academica-e.unavarra.es/handle/2454/42142
dc.language.isoengen
dc.publisherSpringeren
dc.relation.ispartofSensors and Microsystems. AISEM 2019. Lecture Notes in Electrical Engineering, vol 629en
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/1PE/TEC2016-78047-R/
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/1PE/TEC2016-79367-C2-2-R/
dc.relation.publisherversionhttps://doi.org/10.1007/978-3-030-37558-4_49
dc.rights© Springer Nature Switzerland AG 2020en
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.subjectLossy mode resonanceen
dc.subjectIn-fiber optical sensing platformen
dc.subjectNanofilm depositionen
dc.subjectFemtomolar concentrationen
dc.subjectReusabilityen
dc.titleLossy mode resonance enabling ultra-low detection limit for fibre-optic biosensors (INVITED)en
dc.typeinfo:eu-repo/semantics/conferenceObject
dc.type.versioninfo:eu-repo/semantics/acceptedVersion
dspace.entity.typePublication
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relation.isAuthorOfPublication.latestForDiscovery4af62af3-50fe-47ee-a17c-bd4ffb52ebe3

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