Lossy mode resonance enabling ultra-low detection limit for fibre-optic biosensors (INVITED)

Date

2020

Authors

Director

Publisher

Springer
Acceso abierto / Sarbide irekia
Contribución a congreso / Biltzarrerako ekarpena
Versión aceptada / Onetsi den bertsioa

Project identifier

  • ES/1PE/TEC2016-78047-R/
  • ES/1PE/TEC2016-79367-C2-2-R/
Impacto

Abstract

The combination of optical fibre-based biosensors with nanotechnologies is providing the opportunity for the development of in situ, portable, lightweight, versatile and high-sensitivity optical sensing platforms. We report on the generation of lossy mode resonances (LMRs) by means of the deposition of nm-thick SnO2 film on optical fibres. This allows measuring precisely and accurately the changes in refractive index of the fibre-surrounding medium with very high sensitivity compared to other optical technology platforms, such as long period grating or surface plasmon resonance. This approach, mixed with the use of specialty fiber structures such as Dshaped fibres, allows improving the light-matter interaction in strong way. Different imaging systems, i.e. SEM and TEM along with X-EDS tool, have been used to study the optical features of the fiber coating. The shift of the LMR has been monitored in real-time thanks to conventional wavelength interrogation system and ad hoc developed microfluidics. A big leap in performance has been attained by detecting femtomolar concentrations in human serum. The biosensor reusability has been also tested by using a solution of sodium dodecyl sulphate.

Description

Keywords

Lossy mode resonance, In-fiber optical sensing platform, Nanofilm deposition, Femtomolar concentration, Reusability

Department

Ingeniaritza Elektrikoa, Elektronikoaren eta Telekomunikazio Ingeniaritzaren / Institute of Smart Cities - ISC / Ingeniería Eléctrica, Electrónica y de Comunicación

Faculty/School

Degree

Doctorate program

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