• The impact of the covid-19 pandemic on mental disorders. A critical review 

      Clemente Suárez, Vicente Javier; Martínez-González, Marina Begoña; Benítez Agudelo, Juan Camilo; Navarro Jiménez, Eduardo; Beltrán Velasco, Ana Isabel; Ruisoto, Pablo Upna Orcid; Díaz Arroyo, Esperanza; Laborde Cárdenas, Carmen Cecilia; Tornero Aguilera, José Francisco (MDPI, 2021)   Artículo / Artikulua  OpenAccess
      The COVID-19 pandemic has impacted the lives of the worldwide population. Citizens suffer the social, economic, physiological, and psychological effects of this pandemic. Primary sources, scientific articles, and secondary ...
    • The impact of two-component sensorial network in staphylococcal speciation 

      Rapún Araiz, Beatriz Upna Orcid; Haag, Andreas F.; Solano Goñi, Cristina Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid (Elsevier, 2020)   Artículo / Artikulua  OpenAccess
      Bacteria use two-component systems (TCSs) to sense and respond to their environments. Free-living bacteria usually contain dozens of TCSs, each of them responsible for sensing and responding to a different range of signals. ...
    • Impact on physical function of the +AGIL Barcelona program in community-dwelling older adults with cognitive impairment: an interventional cohort study 

      Arnal, Cristina; Pérez, Mónica L.; Soto, Luis; Casas Herrero, Álvaro Upna; Ars, Joan; Baró, Sonia; Díaz, Francisco; Abilla, Araceli; Enfedaque, M Belén; Cesari, Matteo; Inzitari, Marco (BMC, 2023)   Artículo / Artikulua  OpenAccess
      Background: Older adults with cognitive impairment (CI) have higher multimorbidity and frailty prevalence, lower functional status and an increased likelihood to develop dementia, non-cognitive deficits, and adverse ...
    • Impaired LXRα phosphorylation attenuates progression of fatty liver disease 

      Bécares, Natalia; Gage, Matthew C.; Voisin, Maud; Shrestha, Elina; Martín-Gutiérrez, Lucía; Liang, Ning; Louie, Rikah; Pourcet, Benoît; Pello, Óscar M.; Luong, Tu Vinh; Goñi Irigoyen, Saioa Upna Orcid; Pichardo-Almarza, César; Røberg-Larsen, Hanne; Díaz-Zuccarini, Vanessa; Steffensen, Knut R.; O’Brien, Alastair; Garabedian, Michael J.; Rombouts, Krista; Treuter, Eckardt; Pineda-Torra, Inés (Cell Press, 2019)   Artículo / Artikulua  OpenAccess
      Non-alcoholic fatty liver disease (NAFLD) is a very common indication for liver transplantation. How fat-rich diets promote progression from fatty liver to more damaging inflammatory and fibrotic stages is poorly understood. ...
    • Impairment of pre-mRNA splicing in liver disease: Mechanisms and consequences 

      Berasain, Carmen; Goñi Irigoyen, Saioa Upna Orcid; Castillo, Josefa; Latasa, Maria Ujue; Prieto, Jesús; Ávila, Matías A. (Baishideng Publishing Group, 2010)   Artículo / Artikulua  OpenAccess
      Pre-mRNA splicing is an essential step in the process of gene expression in eukaryotes and consists of the removal of introns and the linking of exons to generate mature mRNAs. This is a highly regulated mechanism that ...
    • Implementando un registro poblacional de enfermedades raras en España: la experiencia de Navarra 

      Vicente Cemborain, Esther Upna Orcid; Guevara Eslava, Marcela; Lasanta Sáez, María José Upna; Ramos Arroyo, María A.; Ardanaz, Eva (Ministerio de Sanidad y Consumo, 2018)   Artículo / Artikulua  OpenAccess
      In 2012, the Spanish Rare Disease Registries Research Network (Spain-RDR) was consolidated with the aim of creating a Spanish population- based Rare Diseases Registry. In order to achieve this, each of the 17 Spanish Regions ...
    • Improvement of cognitive function in wild-type and Alzheimer's disease mouse models by the immunomodulatory properties of menthol inhalation or by depletion of T regulatory cells 

      Casares, Noelia; Alfaro Larraya, María Upna; Cuadrado-Tejedor, Mar; Lasarte-Cía, Aritz; Navarro Negredo, Flor; Vivas, Isabel; Espelosín, María; Cartas-Cejudo, Paz; Fernández Irigoyen, Joaquín Upna Orcid; Santamaría, Enrique; García-Osta, Ana; Lasarte, Juan José (Frontiers Media, 2023)   Artículo / Artikulua  OpenAccess
      A complex network of interactions exists between the olfactory, immune and central nervous systems. In this work we intend to investigate this connection through the use of an immunostimulatory odorant like menthol, analyzing ...
    • In vitro assessment of the role of p53 on chemotherapy treatments in neuroblastoma cell lines 

      Blanco Luquin, Idoia; Lázcoz, Paula Upna; Celay Leoz, Ion Upna; Castresana, Javier S.; Encío Martínez, Ignacio Upna Orcid (MDPI, 2021)   Artículo / Artikulua  OpenAccess
      Neuroblastoma is the most frequent malignant extracranial solid tumor of infancy. The overall objective of this work consists of determining the presence of alterations in the p53/MDM2 /p14ARF signaling pathway in neuroblastoma ...
    • Incidence of type 1 diabetes mellitus in children and adolescents under 20 years of age across 55 countries from 2000 to 2022: a systematic review with meta-analysis 

      Hormazábal Aguayo, Ignacio; Ezzatvar, Yasmin; Huerta Uribe, Nidia; Ramírez Vélez, Robinson; Izquierdo Redín, Mikel; García Hermoso, Antonio (Wiley, 2023)   Artículo / Artikulua  OpenAccess
      Aims: the aim of this study was to determine the global incidence of type 1 diabetes mellitus (T1DM) in children and adolescents under 20 years of age from 2000 to 2022. Materials and methods: two reviewers searched three ...
    • Incidence, hospitalization, mortality and risk factors of COVID-19 in long-term care residential homes for patients with chronic mental illness 

      Arnedo Pena, Alberto; Romeu García, María Ángeles; Gasco-Laborda, Juan Carlos; Meseguer-Ferrer, Noemí; Safont-Adsuara, Lourdes; Guillén Grima, Francisco; Tirado-Balaguer, María Dolores; Sabater-Vidal, Susana; Gil-Fortuño, María; Pérez-Olaso, Óscar; Hernández-Pérez, Noelia; Moreno-Muñoz, Rosario; Bellido Blasco, Juan (MDPI, 2022)   Artículo / Artikulua  OpenAccess
      Long-term care residential homes (LTCRH) for patients with chronic mental illness have suffered the enormous impact of COVID-19. This study aimed to estimate incidence, hospitalization, mortality, and risk factors of ...
    • Incidencia de caídas en el hospital de larga-media estancia. Factores de riesgo y estrategias para la prevención 

      Cáceres Santana, E.; Bermúdez Moreno, C.; Ramírez Suarez, J.; Bahamonde Román, C.; Murie Fernández, Manuel (Elsevier, 2022)   Artículo / Artikulua  OpenAccess
      Introducción: Las caídas son un problema de salud importante en ancianos institucionalizados debido a su alta morbimortalidad y a su relación con la calidad de vida futura. Objetivo: Analizar la incidencia de caídas, el ...
    • Increased C-X-C motif chemokine ligand 12 levels in cerebrospinal fluid as a candidate biomarker in sporadic amyotrophic lateral sclerosis 

      Andrés Benito, Pol; Povedano, Mónica; Domínguez Rubio, Raúl; Marco, Carla; Colomina, María J.; López-Pérez, Óscar; Santana, Isabel; Baldeiras, Inês; Martínez-Yelámos, Sergio; Zerr, Inga; Llorens, Franc; Fernández Irigoyen, Joaquín Upna Orcid; Santamaría, Enrique; Ferrer, Isidro (MDPI, 2020)   Artículo / Artikulua  OpenAccess
      Sporadic amyotrophic lateral sclerosis (sALS) is a fatal progressive neurodegenerative disease affecting upper and lower motor neurons. Biomarkers are useful to facilitate the diagnosis and/or prognosis of patients and to ...
    • Increased PIO2 at exhaustion in hypoxia enhaces muscle activation and swifty relieves fatigue: a placebo or a PIO2 dependent effect? 

      Torres Peralta, Rafael; Losa Reyna, José; Morales Alamo, David; González Izal, Miriam Upna; Pérez Suárez, Ismael; Ponce González, Jesús G.; Izquierdo Redín, Mikel Upna Orcid; Calbet, José A. L. (Frontiers Media, 2016)   Artículo / Artikulua  OpenAccess
      To determine the level of hypoxia from which muscle activation (MA) is reduced during incremental exercise to exhaustion (IE), and the role played by PIO2 in this process, ten volunteers (21 ± 2 years) performed four IE ...
    • Individual trajectories of cognitive performance in first episode psychosis: a 2-year follow-up study 

      Sánchez Torres, Ana María Upna Orcid; Moreno-Izco, Lucía; Lorente Omeñaca, Ruth; Cabrera, Bibiana; Lobo, Antonio; González Pinto, Ana; Merchán-Naranjo, Jessica; Corripio, Iluminada; Vieta, Eduard; Serna, Elena de la; Butjosa, Anna; Contreras, Fernando; Sarró, Salvador; Mezquida, Gisela; Ribeiro Fernández, María; Bernardo, Miguel; Cuesta, Manuel J.; PEPs Group (Springer, 2018)   Artículo / Artikulua  OpenAccess
      Individual changes over time in cognition in patients with psychotic disorders have been studied very little, especially in the case of frst episode psychosis (FEP). We aimed to establish whether change in individual ...
    • Individual- and community-level determinants of maternal health service utilization in southern Ethiopia: a multilevel analysis 

      Yoseph, Amanuel; Teklesilasie, Wondwosen; Guillén Grima, Francisco; Astatkie, Ayalew (SAGE, 2023)   Artículo / Artikulua  OpenAccess
      Background: Maternal health service utilization decreases maternal morbidity and mortality. However, the existing evidence is inadequate to design effective intervention strategies in Ethiopia. Objectives: This study aimed ...
    • Infant mortality in the European Union: a time trend analysis of the 1994-2015 period 

      Onambele, Luc; San Martín Rodríguez, Leticia Upna Orcid; Niu, Hao; Álvarez Álvarez, Ismael; Arnedo Pena, Alberto; Guillén Grima, Francisco Upna Orcid; Aguinaga Ontoso, Inés Upna Orcid (Elsevier España, 2019)   Artículo / Artikulua  OpenAccess
      Introducción: La mortalidad infantil es un indicador de la salud infantil y una variable explicativa del desarrollo socioeconómico. Nuestro objetivo fue examinar los cambios y tendencias de la mortalidad infantil en la ...
    • Inflammation in COVID-19 and the effects of non-pharmacological interventions during the pandemic: a review 

      Clemente Suárez, Vicente Javier; Bustamante Sanchez, Álvaro; Tornero Aguilera, José Francisco; Ruisoto, Pablo Upna Orcid; Mielgo Ayuso, Juan (MDPI, 2022)   Artículo / Artikulua  OpenAccess
      Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused the coronavirus disease 2019 (COVID-19) pandemic that hit the health systems worldwide hard, causing a collapse of healthcare systems. One of the main ...
    • The influence of ACE ID and ACTN3 R577X polymorphisms on lower-extremity function in older women in response to high-speed power training 

      Pereira, Ana; Costa, Aldo M.; Leitão, José C.; Monteiro, António M.; Izquierdo Redín, Mikel Upna Orcid; Silva, António J.; Bastos, Estela; Marqués, Mário C. (BioMed Central, 2013)   Artículo / Artikulua  OpenAccess
      Background: We studied the influence of the ACE I/D and ACTN3 R577X polymorphisms (single or combined) on lower-extremity function in older women in response to high-speed power training. Methods: One hundred and thirty-nine ...
    • Influence of diabetes mellitus on the pathological profile of aortic stenosis: a sex-based approach 

      Martín Núñez, Ernesto; Goñi Olóriz, Miriam; Matilla Cuenca, Lara; Garaikoetxea Zubillaga, Mattie; Mourino-Álvarez, Laura; Navarro, Adela; Fernández Celis, Amaya; Tamayo Rodríguez, Ibai; Gaínza Calleja, Alicia; Álvarez, Virginia; Sádaba Sagredo, Rafael; Barderas, María G.; Jover, Eva; López Andrés, Natalia (Springer Nature, 2023)   Artículo / Artikulua  OpenAccess
      Background: Diabetes mellitus (DM) accelerates the progression of aortic stenosis (AS), but how their underlying molecular mechanisms interact is not clear. Moreover, whether DM contributes to clinically relevant sex-differences ...
    • Influence of short-term training on functional capacity and (anti-)inflammatory immune signalling in acute hospitalization 

      Ramírez Vélez, Robinson Upna Orcid; Martínez Velilla, Nicolás Upna Orcid; Fernández Irigoyen, Joaquín Upna Orcid; Santamaría, Enrique; Izquierdo Redín, Mikel Upna Orcid; Palomino Echeverría, Sara Upna Orcid (Wiley, 2020)   Artículo / Artikulua  OpenAccess
      To investigate the infuence of exercise on inflammatory signalling, it was performed cytokine array profiling in human serum to identify inflammatory cytokines produced after a 3 day in-hospital intervention including ...

      El Repositorio ha recibido la ayuda de la Fundación Española para la Ciencia y la Tecnología para la realización de actividades en el ámbito del fomento de la investigación científica de excelencia, en la Línea 2. Repositorios institucionales (convocatoria 2020-2021).
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