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La sanidad y la medicina, de la jeringa al scanner
Cuando nace Pregón en 1943 la sanidad y la medicina comienzan a salir del empirismo hacia una medicina científica; y la salud, de ser un intangible a un derecho de los trabajadores. Los hospitales públicos existentes estaban ... -
Satisfacción laboral y factores de mejora en profesionales de atención primaria
Fundamento. La calidad de los servicios en un sistema sanitario está relacionada con el nivel de satisfacción de sus profesionales. El objetivo de este trabajo es conocer la satisfacción laboral y jerarquizar aquellos ... -
Scaffold attachment factor B1 regulates androgen degradation pathways in prostate cancer
The nuclear matrix protein Scaffold Attachment Factor B1 (SAFB1, SAFB) can act in prostate cancer (PCa) as an androgen receptor (AR) co-repressor that functions through epigenetic silencing of AR targets, such as prostate ... -
Schizophrenia and hospital admissions for cardiovascular events in a large population: the APNA study
(1) Background: patients with schizophrenia have higher mortality, with cardiovascular diseases being the first cause of mortality. This study aims to estimate the excess risk of hospital admission for cardiovascular events ... -
Schoolbag weight carriage in Portuguese children and adolescents: a cross-sectional study comparing possible influencing factors
Background Schoolbags and the consequences of carrying them, particularly those associated with overload, are often studied as a health concern. Modifications in gait and posture were reported when children carried loads ... -
Sedentary behaviors and risk of depression in the Seguimiento Universidad de Navarra cohort: the SUN Project
The study aimed to prospectively examine the association between different sedentary behaviors and the risk of depression. We included 12,691 Spanish university graduates (mean age: 36.7 year; SD: 11.5), participants of ... -
Seleno-analogs of scaffolds resembling natural products a novel warhead toward dual compounds
Nowadays, oxidative cell damage is one of the common features of cancer and Alzheimer’s disease (AD), and Se-containing molecules, such as ebselen, which has demonstrated strong antioxidant activity, have demonstrated ... -
Self-assembling protein nanoparticles in the design of vaccines: 2022 update
Vaccines constitute a pillar in the prevention of infectious diseases. The unprecedented emergence of novel immunization strategies due to the COVID-19 pandemic has again positioned vaccination as a pivotal measure to ... -
Sequencing effects of plyometric training applied before or after regular soccer training on measures of physical fitness in young players
(Lippincott, Williams & WilkinsNational Strength and Conditioning Association, 2020) Artículo / ArtikuluaTo compare the effects of short-term (i.e., 7 weeks) plyometric jump training applied before (PJT-B) or after (PJT-A) soccer practice on components of physical fitness in young soccer players, a single-blind randomized ... -
Sex differences in the association between dynapenic abdominal obesity and onset of disability in activities of daily living among adults aged ≥50 years: a prospective analysis of the Irish longitudinal study on ageing
Background: Sex differences in the longitudinal relationship between dynapenic abdominal obesity, i.e., impairment in muscle strength and high waist circumference, and disability in activities of daily living have not been ... -
Sex-dependent expression of neutrophil gelatinase-associated lipocalin in aortic stenosis
Background: Accumulating evidence suggest the existence of sex-related differences in the pathogenesis of aortic stenosis (AS) with inflammation, oxidative stress, fibrosis and calcification being over-represented in men. ... -
Sex-divergent effects on the NAD+-dependent deacetylase sirtuin signaling across the olfactory-entorhinal-amygdaloid axis in Alzheimer's and Parkinson's diseases
Background Smell impairment is one of the earliest features in Alzheimer’s (AD) and Parkinson’s diseases (PD). Due to sex diferences exist in terms of smell and olfactory structures as well as in the prevalence and ... -
Sex-specific dose-response effects of a 24-week supervised concurrent exercise intervention on cardiorespiratory fitness and muscular strength in young adults: The ACTIBATE randomized controlled trial
Concurrent training has been postulated as an appropriate time-efficient strategy to improve physical fitness, yet whether the exercise-induced adaptations are similar in men and women is unknown. An unblinded randomized ... -
Sexual functioning, desire, and satisfaction in women with TBI and healthy controls
Traumatic brain injury (TBI) can substantially alter many areas of a person’s life and there has been little research published regarding sexual functioning in women with TBI. Methods. A total of 58 women (29 with TBI and ... -
Sharing good NEWS across the world: developing comparable scores across 12 countries for the neighborhood environment walkability scale (NEWS)
Background: The IPEN (International Physical Activity and Environment Network) Adult project seeks to conduct pooled analyses of associations of perceived neighborhood environment, as measured by the Neighborhood Environment ... -
Short-term effects of manipulative treatment versus a therapeutic home exercise protocol for chronic cervical pain: a randomized clinical trial
Background: While both manipulative treatment and physical exercises are used to treat cervical pain, it remains unclear which is most effective. Objective: To compare the short-term effects of high-velocity, low-amplitude ... -
Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer
Drug combinations are key to circumvent resistance mechanisms compromising response to single anti-cancer targeted therapies. The implementation of combinatorial approaches involving MEK1/2 or KRASG12C inhibitors in the ... -
El silencio social que se construye en torno al aborto inducido
Objetivo: analizar la experiencia de las mujeres que han tenido un aborto y las consecuencias dolorosas que dicha práctica produce en la vida y en el cuerpo de las mujeres, así como averiguar si existe un apoyo social para ... -
Similar cardiometabolic effects of high- and moderate-intensity training among apparently healthy inactive adults: a randomized clinical trial
Background: Metabolic syndrome (MetS) increases the risk of morbidity and mortality from cardiovascular disease, and exercise training is an important factor in the treatment and prevention of the clinical components of ... -
Simulación clínica y la pandemia por COVID-19. ¿De dónde venimos? ¿Hacia dónde queremos ir?
Se trata el tema de la simulación clínica y se pone de manifiesto sus ventajas en actividad clínica consecuencia de la pandemia de Covid-19, esbozando la situación actual y las perspectivas de futuro.