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Study of compartmentalization in the visna clinical form of small ruminant lentivirus infection in sheep
(BioMed Central, 2012)
Artículo / Artikulua,
Background: A central nervous system (CNS) disease outbreak caused by small ruminant lentiviruses (SRLV) has triggered interest in Spain due to the rapid onset of clinical signs and relevant production losses. In a previous ...
The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition
(Public Library of Science, 2012)
Artículo / Artikulua,
Innate immunity recognizes bacterial molecules bearing pathogen-associated molecular patterns to launch inflammatory responses leading to the activation of adaptive immunity. However, the lipopolysaccharide (LPS) of the ...
The extradomain a of fibronectin enhances the efficacy of lipopolysaccharide defective Salmonella bacterins as vaccines in mice
(BioMed Central, 2012)
Artículo / Artikulua,
The Extradomain A from fibronectin (EDA) has an immunomodulatory role as fusion protein with viral and tumor antigens, but its effect when administered with bacteria has not been assessed. Here, we investigated the adjuvant ...
What have we learned from brucellosis in the mouse model?
(BioMed Central, 2012)
Artículo / Artikulua,
Brucellosis is a zoonosis caused by Brucella species. Brucellosis research in natural hosts is often precluded by practical, economical and ethical reasons and mice are widely used. However, mice are not natural Brucella ...
Mannose receptor may be involved in small ruminant lentivirus pathogenesis
(BioMed Central, 2012)
info:eu-repo/semantics/article,
Thirty-one sheep naturally infected with small ruminant lentiviruses (SRLV) of known genotype (A or B), and clinically affected with neurological disease, pneumonia or arthritis were used to analyse mannose receptor (MR) ...
Wavelet-based detection of transcriptional activity on a novel Staphylococcus aureus tiling microarray
(BioMed Central, 2012)
info:eu-repo/semantics/article,
Background: High-density oligonucleotide microarray is an appropriate technology for genomic analysis, and is particulary useful in the generation of transcriptional maps, ChIP-on-chip studies and re-sequencing of the ...
Bap, a biofilm matrix protein of Staphylococcus aureus prevents cellular internalization through binding to GP96 host receptor
(Public Library of Science, 2012)
Artículo / Artikulua,
The biofilm matrix, composed of exopolysaccharides, proteins, nucleic acids and lipids, plays a well-known role as a defence
structure, protecting bacteria from the host immune system and antimicrobial therapy. However, ...
An effort to make sense of antisense transcription in bacteria
(Taylor & Francis, 2012)
Artículo / Artikulua,
Analysis of bacterial transcriptomes have shown the existence of a genome-wide process of overlapping transcription due to the presence of antisense RNAs, as well as mRNAs that overlapped in their entire length or in some ...
Salmonella biofilm development depends on the phosphorylation status of RcsB
(American Society for Microbiology, 2012)
Artículo / Artikulua,
The Rcs phosphorelay pathway is a complex signaling pathway involved in the regulation of many cell surface structures in enteric
bacteria. In response to environmental stimuli, the sensor histidine kinase (RcsC) ...
Effect of transcriptional activators SoxS, RobA, and RamA on expression of multidrug efflux pump AcrAB-TolC in enterobacter cloacae
(American Society for Microbiology, 2012)
info:eu-repo/semantics/article,
Control of membrane permeability is a key step in regulating the intracellular concentration of antibiotics. Efflux pumps confer innate resistance to a wide range of toxic compounds such as antibiotics, dyes, detergents, ...