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The extradomain a of fibronectin enhances the efficacy of lipopolysaccharide defective Salmonella bacterins as vaccines in mice
(BioMed Central, 2012)
Artículo / Artikulua,
The Extradomain A from fibronectin (EDA) has an immunomodulatory role as fusion protein with viral and tumor antigens, but its effect when administered with bacteria has not been assessed. Here, we investigated the adjuvant ...
Wavelet-based detection of transcriptional activity on a novel Staphylococcus aureus tiling microarray
(BioMed Central, 2012)
info:eu-repo/semantics/article,
Background: High-density oligonucleotide microarray is an appropriate technology for genomic analysis, and is particulary useful in the generation of transcriptional maps, ChIP-on-chip studies and re-sequencing of the ...
Coordinated cyclic-di-GMP repression of salmonella motility through YcgR and cellulose
(American Society for Microbiology, 2013)
Artículo / Artikulua,
Cyclic di-GMP (c-di-GMP) is a secondary messenger that controls a variety of cellular processes, including the switch between a biofilm and a planktonic bacterial lifestyle. This nucleotide binds to cellular effectors in ...
Bap, a biofilm matrix protein of Staphylococcus aureus prevents cellular internalization through binding to GP96 host receptor
(Public Library of Science, 2012)
Artículo / Artikulua,
The biofilm matrix, composed of exopolysaccharides, proteins, nucleic acids and lipids, plays a well-known role as a defence
structure, protecting bacteria from the host immune system and antimicrobial therapy. However, ...
Overlapping transcription and bacterial RNA removal
(National Academy of Sciences, 2014)
Artículo / Artikulua,
The precise understanding of the biology of a living cell requires the identification and quantification of the molecular components necessary to sustain life. One such element is RNA. Two independent high-throughput ...
Salmonella biofilm development depends on the phosphorylation status of RcsB
(American Society for Microbiology, 2012)
Artículo / Artikulua,
The Rcs phosphorelay pathway is a complex signaling pathway involved in the regulation of many cell surface structures in enteric
bacteria. In response to environmental stimuli, the sensor histidine kinase (RcsC) ...
Biofilm switch and immune response determinants at early stages of infection
(Elsevier (Cell Press), 2013)
Artículo / Artikulua,
Biofilm development is recognized as a major virulence factor underlying most chronic bacterial infections. When a biofilm community is established, planktonic cells growing in the surroundings of a tissue switch to a ...
Staphylococcal Bap proteins build amyloid scaffold biofilm matrices in response to environmental signals
(Public Library of Science, 2016)
Artículo / Artikulua,
Major components of the biofilm matrix scaffold are proteins that assemble to create a unified structure that maintain bacteria attached to each other and to surfaces. We provide evidence that a surface protein present in ...
Genome-wide antisense transcription drives mRNA processing in bacteria
(National Academy of Sciences, 2011)
Artículo / Artikulua,
RNA deep sequencing technologies are revealing unexpected levels of complexity in bacterial transcriptomes with the discovery of abundant noncoding RNAs, antisense RNAs, long 5′ and 3′ untranslated regions, and alternative ...
An effort to make sense of antisense transcription in bacteria
(Taylor & Francis, 2012)
Artículo / Artikulua,
Analysis of bacterial transcriptomes have shown the existence of a genome-wide process of overlapping transcription due to the presence of antisense RNAs, as well as mRNAs that overlapped in their entire length or in some ...