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Small ruminant macrophage polarization may play a pivotal role on lentiviral infection
(BioMed Central, 2013)
info:eu-repo/semantics/article,
Small ruminant lentiviruses (SRLV) infect the monocyte/macrophage lineage inducing a long-lasting infection affecting body condition, production and welfare of sheep and goats all over the world. Macrophages play a pivotal ...
Identification of the ovine mannose receptor and its possible role in Visna/Maedi virus infection
(BioMed Central, 2011)
info:eu-repo/semantics/article,
This study aims to characterize the mannose receptor (MR) gene in sheep and its role in ovine visna/maedi virus (VMV) infection. The deduced amino acid sequence of ovine MR was compatible with a transmembrane protein having ...
Mannose receptor may be involved in small ruminant lentivirus pathogenesis
(BioMed Central, 2012)
info:eu-repo/semantics/article,
Thirty-one sheep naturally infected with small ruminant lentiviruses (SRLV) of known genotype (A or B), and clinically affected with neurological disease, pneumonia or arthritis were used to analyse mannose receptor (MR) ...
Study of compartmentalization in the visna clinical form of small ruminant lentivirus infection in sheep
(BioMed Central, 2012)
Artículo / Artikulua,
Background: A central nervous system (CNS) disease outbreak caused by small ruminant lentiviruses (SRLV) has triggered interest in Spain due to the rapid onset of clinical signs and relevant production losses. In a previous ...
The extradomain a of fibronectin enhances the efficacy of lipopolysaccharide defective Salmonella bacterins as vaccines in mice
(BioMed Central, 2012)
Artículo / Artikulua,
The Extradomain A from fibronectin (EDA) has an immunomodulatory role as fusion protein with viral and tumor antigens, but its effect when administered with bacteria has not been assessed. Here, we investigated the adjuvant ...
Immunization against small ruminant lentiviruses
(MDPI, 2013)
Artículo / Artikulua,
Multisystemic disease caused by Small Ruminant Lentiviruses (SRLV) in sheep and goats leads to production losses, to the detriment of animal health and welfare. This, together with the lack of treatments, has triggered ...
Small ruminant lentiviruses: genetic variability, tropism and diagnosis
(MDPI, 2013)
info:eu-repo/semantics/article,
Small ruminant lentiviruses (SRLV) cause a multisystemic chronic disease affecting animal production and welfare. SRLV infections are spread across the world with the exception of Iceland. Success in controlling SRLV spread ...
Characterization of ovine A3Z1 restriction properties against small ruminant lentiviruses (SRLVs)
(MDPI, 2017)
info:eu-repo/semantics/article,
Intrinsic factors of the innate immune system include the apolipoprotein B editing
enzyme catalytic polypeptide-like 3 (APOBEC3) protein family. APOBEC3 inhibits replication of
different virus families by cytosine ...
Lack of relationship between Visna/maedi infection and scrapie resistance genetic markers
(Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria (INIA), 2014)
info:eu-repo/semantics/article,
The relationship between Visna/maedi virus (VMV) antibody status and scrapie genetic resistance of 10,611 Rasa
Aragonesa sheep from 17 flocks in Aragón (Spain) was investigated. The fifteen most common PRNP gene haplotypes
and ...
Post-entry blockade of small ruminant lentiviruses by wild ruminants
(BioMed Central, 2016)
Artículo / Artikulua,
Small ruminant lentivirus (SRLV) infection causes losses in the small ruminant industry due to reduced animal production
and increased replacement rates. Infection of wild ruminants in close contact with infected domestic ...