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Small ruminant macrophage polarization may play a pivotal role on lentiviral infection
(BioMed Central, 2013)
info:eu-repo/semantics/article,
Small ruminant lentiviruses (SRLV) infect the monocyte/macrophage lineage inducing a long-lasting infection affecting body condition, production and welfare of sheep and goats all over the world. Macrophages play a pivotal ...
Identification of the ovine mannose receptor and its possible role in Visna/Maedi virus infection
(BioMed Central, 2011)
info:eu-repo/semantics/article,
This study aims to characterize the mannose receptor (MR) gene in sheep and its role in ovine visna/maedi virus (VMV) infection. The deduced amino acid sequence of ovine MR was compatible with a transmembrane protein having ...
Mannose receptor may be involved in small ruminant lentivirus pathogenesis
(BioMed Central, 2012)
info:eu-repo/semantics/article,
Thirty-one sheep naturally infected with small ruminant lentiviruses (SRLV) of known genotype (A or B), and clinically affected with neurological disease, pneumonia or arthritis were used to analyse mannose receptor (MR) ...
Study of compartmentalization in the visna clinical form of small ruminant lentivirus infection in sheep
(BioMed Central, 2012)
Artículo / Artikulua,
Background: A central nervous system (CNS) disease outbreak caused by small ruminant lentiviruses (SRLV) has triggered interest in Spain due to the rapid onset of clinical signs and relevant production losses. In a previous ...
Characterization of ovine A3Z1 restriction properties against small ruminant lentiviruses (SRLVs)
(MDPI, 2017)
info:eu-repo/semantics/article,
Intrinsic factors of the innate immune system include the apolipoprotein B editing
enzyme catalytic polypeptide-like 3 (APOBEC3) protein family. APOBEC3 inhibits replication of
different virus families by cytosine ...
Post-entry blockade of small ruminant lentiviruses by wild ruminants
(BioMed Central, 2016)
Artículo / Artikulua,
Small ruminant lentivirus (SRLV) infection causes losses in the small ruminant industry due to reduced animal production
and increased replacement rates. Infection of wild ruminants in close contact with infected domestic ...
Ovine TRIM5α can restrict visna/maedi virus
(American Society for Microbiology, 2012)
info:eu-repo/semantics/article,
The restrictive properties of tripartite motif-containing 5 alpha (TRIM5α) from small ruminant species have not been explored.
Here, we identify highly similar TRIM5α sequences in sheep and goats. Cells transduced with ...
Detection of PrPSc in lung and mammary gland is favored by the presence of Visna/maedi virus lesions in naturally coinfected sheep
(EDP Sciences, 2010)
info:eu-repo/semantics/article,
There are few reports on the pathogenesis of scrapie (Sc) and Visna/maedi virus (VMV)
coinfections. The aim of this work was to study in vivo as well as post mortem both diseases in 91 sheep.
Diagnosis of Sc and VMV ...